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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NUAK2 All Species: 15.76
Human Site: S327 Identified Species: 28.89
UniProt: Q9H093 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H093 NP_112214.1 628 69612 S327 G G H P G S D S A R A S M A D
Chimpanzee Pan troglodytes XP_001161041 661 74289 L352 T E A K M K G L A K P T T S E
Rhesus Macaque Macaca mulatta XP_001088883 675 74111 S327 G G H P G S D S A R A S M A D
Dog Lupus familis XP_545687 631 69738 D331 E G G P P G S D S G R A S V A
Cat Felis silvestris
Mouse Mus musculus Q8BZN4 639 70657 F339 G G H P S G D F G R A S M A D
Rat Rattus norvegicus Q66HE5 630 69934 S331 G G H P S G D S G R A S M A D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515855 679 75174 S373 G G G G S S E S P L A S V A D
Chicken Gallus gallus Q9IA88 798 88848 T380 E M P Q D S L T S E T L R S S
Frog Xenopus laevis NP_001088596 570 64876 L284 N W G Y T Q P L A E Q E P C K
Zebra Danio Brachydanio rerio Q6NSM8 1187 130949 A370 D S Y D H Y S A T Y S L L S D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9TW45 1192 126331 S543 P S R Y S R S S A T A T G A S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P92958 512 58671 L226 D D E N I P N L F K K I K G G
Baker's Yeast Sacchar. cerevisiae P06782 633 72027 S332 E E N E N N D S K K D G S S P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 53.8 82 86.6 N.A. 85.4 85.7 N.A. 68.7 28.8 51.4 22.5 N.A. N.A. N.A. 22.1 N.A.
Protein Similarity: 100 65.9 84.5 90.1 N.A. 89.5 90.9 N.A. 75.8 43.4 64 33.4 N.A. N.A. N.A. 34.4 N.A.
P-Site Identity: 100 6.6 100 13.3 N.A. 73.3 80 N.A. 53.3 6.6 6.6 6.6 N.A. N.A. N.A. 26.6 N.A.
P-Site Similarity: 100 33.3 100 26.6 N.A. 73.3 80 N.A. 66.6 26.6 6.6 40 N.A. N.A. N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 29.4 25.9 N.A.
Protein Similarity: N.A. N.A. N.A. 46.5 44.7 N.A.
P-Site Identity: N.A. N.A. N.A. 0 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 0 0 8 39 0 47 8 0 47 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 16 8 0 8 8 0 39 8 0 0 8 0 0 0 47 % D
% Glu: 24 16 8 8 0 0 8 0 0 16 0 8 0 0 8 % E
% Phe: 0 0 0 0 0 0 0 8 8 0 0 0 0 0 0 % F
% Gly: 39 47 24 8 16 24 8 0 16 8 0 8 8 8 8 % G
% His: 0 0 31 0 8 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 0 0 0 0 0 8 0 0 0 % I
% Lys: 0 0 0 8 0 8 0 0 8 24 8 0 8 0 8 % K
% Leu: 0 0 0 0 0 0 8 24 0 8 0 16 8 0 0 % L
% Met: 0 8 0 0 8 0 0 0 0 0 0 0 31 0 0 % M
% Asn: 8 0 8 8 8 8 8 0 0 0 0 0 0 0 0 % N
% Pro: 8 0 8 39 8 8 8 0 8 0 8 0 8 0 8 % P
% Gln: 0 0 0 8 0 8 0 0 0 0 8 0 0 0 0 % Q
% Arg: 0 0 8 0 0 8 0 0 0 31 8 0 8 0 0 % R
% Ser: 0 16 0 0 31 31 24 47 16 0 8 39 16 31 16 % S
% Thr: 8 0 0 0 8 0 0 8 8 8 8 16 8 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 0 % V
% Trp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 16 0 8 0 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _