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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NUAK2 All Species: 22.12
Human Site: S377 Identified Species: 40.56
UniProt: Q9H093 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H093 NP_112214.1 628 69612 S377 R Q H S L K K S R K E N D M A
Chimpanzee Pan troglodytes XP_001161041 661 74289 K402 K R P K G I L K K R S N S E H
Rhesus Macaque Macaca mulatta XP_001088883 675 74111 S377 R Q H S L K K S R K E N D M A
Dog Lupus familis XP_545687 631 69738 S381 R Q H S L K K S R K E N D M A
Cat Felis silvestris
Mouse Mus musculus Q8BZN4 639 70657 S389 R Q H S L K K S R K E N D M A
Rat Rattus norvegicus Q66HE5 630 69934 S381 R Q H S L K K S R K E N D M A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515855 679 75174 S423 R Q C S L K K S R K E H D V T
Chicken Gallus gallus Q9IA88 798 88848 N430 N F N G L F R N R S I S P S S
Frog Xenopus laevis NP_001088596 570 64876 Q334 P G G T I T R Q R S L K R S K
Zebra Danio Brachydanio rerio Q6NSM8 1187 130949 Q420 Q L I N P E N Q I V E T D G P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9TW45 1192 126331 A593 N D A A A T A A G G T V V M S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P92958 512 58671 L276 H R W F Q T H L P R Y L A V S
Baker's Yeast Sacchar. cerevisiae P06782 633 72027 A382 A F N E I R D A Y M L I K E N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 53.8 82 86.6 N.A. 85.4 85.7 N.A. 68.7 28.8 51.4 22.5 N.A. N.A. N.A. 22.1 N.A.
Protein Similarity: 100 65.9 84.5 90.1 N.A. 89.5 90.9 N.A. 75.8 43.4 64 33.4 N.A. N.A. N.A. 34.4 N.A.
P-Site Identity: 100 6.6 100 100 N.A. 100 100 N.A. 73.3 13.3 6.6 13.3 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 33.3 100 100 N.A. 100 100 N.A. 86.6 46.6 26.6 33.3 N.A. N.A. N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 29.4 25.9 N.A.
Protein Similarity: N.A. N.A. N.A. 46.5 44.7 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 8 8 0 8 16 0 0 0 0 8 0 39 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 8 0 0 0 0 0 54 0 0 % D
% Glu: 0 0 0 8 0 8 0 0 0 0 54 0 0 16 0 % E
% Phe: 0 16 0 8 0 8 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 8 8 8 0 0 0 8 8 0 0 0 8 0 % G
% His: 8 0 39 0 0 0 8 0 0 0 0 8 0 0 8 % H
% Ile: 0 0 8 0 16 8 0 0 8 0 8 8 0 0 0 % I
% Lys: 8 0 0 8 0 47 47 8 8 47 0 8 8 0 8 % K
% Leu: 0 8 0 0 54 0 8 8 0 0 16 8 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 8 0 0 0 47 0 % M
% Asn: 16 0 16 8 0 0 8 8 0 0 0 47 0 0 8 % N
% Pro: 8 0 8 0 8 0 0 0 8 0 0 0 8 0 8 % P
% Gln: 8 47 0 0 8 0 0 16 0 0 0 0 0 0 0 % Q
% Arg: 47 16 0 0 0 8 16 0 62 16 0 0 8 0 0 % R
% Ser: 0 0 0 47 0 0 0 47 0 16 8 8 8 16 24 % S
% Thr: 0 0 0 8 0 24 0 0 0 0 8 8 0 0 8 % T
% Val: 0 0 0 0 0 0 0 0 0 8 0 8 8 16 0 % V
% Trp: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _