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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NUAK2 All Species: 18.18
Human Site: S416 Identified Species: 33.33
UniProt: Q9H093 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H093 NP_112214.1 628 69612 S416 G I L K K K V S A S A E G V Q
Chimpanzee Pan troglodytes XP_001161041 661 74289 L441 D L C R T G V L L P S S P E A
Rhesus Macaque Macaca mulatta XP_001088883 675 74111 S416 G I L K K K V S A S A E G A Q
Dog Lupus familis XP_545687 631 69738 P420 S I L K K K A P T V E G A R G
Cat Felis silvestris
Mouse Mus musculus Q8BZN4 639 70657 S428 G I L K K K S S T S S G E V Q
Rat Rattus norvegicus Q66HE5 630 69934 S420 G I L K K K A S P S S G E V Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515855 679 75174 S462 G I L K K K T S P P A D G Q K
Chicken Gallus gallus Q9IA88 798 88848 N469 H P I R I P S N T S R R H T L
Frog Xenopus laevis NP_001088596 570 64876 K373 P K K G I L K K T P Q R E S G
Zebra Danio Brachydanio rerio Q6NSM8 1187 130949 P459 H T V G V P D P R A E M Q E D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9TW45 1192 126331 S632 P P S Y K P S S N T T Q I A Q
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P92958 512 58671 S315 D R N Q V L E S L R N R T Q N
Baker's Yeast Sacchar. cerevisiae P06782 633 72027 S421 P P T F Q Q Q S K S H Q K S Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 53.8 82 86.6 N.A. 85.4 85.7 N.A. 68.7 28.8 51.4 22.5 N.A. N.A. N.A. 22.1 N.A.
Protein Similarity: 100 65.9 84.5 90.1 N.A. 89.5 90.9 N.A. 75.8 43.4 64 33.4 N.A. N.A. N.A. 34.4 N.A.
P-Site Identity: 100 6.6 93.3 33.3 N.A. 66.6 66.6 N.A. 60 6.6 0 0 N.A. N.A. N.A. 20 N.A.
P-Site Similarity: 100 26.6 93.3 33.3 N.A. 73.3 73.3 N.A. 73.3 26.6 0 13.3 N.A. N.A. N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 29.4 25.9 N.A.
Protein Similarity: N.A. N.A. N.A. 46.5 44.7 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 16 0 16 8 24 0 8 16 8 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 16 0 0 0 0 0 8 0 0 0 0 8 0 0 8 % D
% Glu: 0 0 0 0 0 0 8 0 0 0 16 16 24 16 0 % E
% Phe: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 39 0 0 16 0 8 0 0 0 0 0 24 24 0 16 % G
% His: 16 0 0 0 0 0 0 0 0 0 8 0 8 0 0 % H
% Ile: 0 47 8 0 16 0 0 0 0 0 0 0 8 0 0 % I
% Lys: 0 8 8 47 54 47 8 8 8 0 0 0 8 0 8 % K
% Leu: 0 8 47 0 0 16 0 8 16 0 0 0 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 0 8 0 0 0 0 8 8 0 8 0 0 0 8 % N
% Pro: 24 24 0 0 0 24 0 16 16 24 0 0 8 0 0 % P
% Gln: 0 0 0 8 8 8 8 0 0 0 8 16 8 16 47 % Q
% Arg: 0 8 0 16 0 0 0 0 8 8 8 24 0 8 0 % R
% Ser: 8 0 8 0 0 0 24 62 0 47 24 8 0 16 0 % S
% Thr: 0 8 8 0 8 0 8 0 31 8 8 0 8 8 0 % T
% Val: 0 0 8 0 16 0 24 0 0 8 0 0 0 24 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _