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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUAK2
All Species:
15.45
Human Site:
S418
Identified Species:
28.33
UniProt:
Q9H093
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H093
NP_112214.1
628
69612
S418
L
K
K
K
V
S
A
S
A
E
G
V
Q
E
D
Chimpanzee
Pan troglodytes
XP_001161041
661
74289
P443
C
R
T
G
V
L
L
P
S
S
P
E
A
E
V
Rhesus Macaque
Macaca mulatta
XP_001088883
675
74111
S418
L
K
K
K
V
S
A
S
A
E
G
A
Q
G
D
Dog
Lupus familis
XP_545687
631
69738
V422
L
K
K
K
A
P
T
V
E
G
A
R
G
D
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BZN4
639
70657
S430
L
K
K
K
S
S
T
S
S
G
E
V
Q
E
D
Rat
Rattus norvegicus
Q66HE5
630
69934
S422
L
K
K
K
A
S
P
S
S
G
E
V
Q
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515855
679
75174
P464
L
K
K
K
T
S
P
P
A
D
G
Q
K
E
E
Chicken
Gallus gallus
Q9IA88
798
88848
S471
I
R
I
P
S
N
T
S
R
R
H
T
L
A
E
Frog
Xenopus laevis
NP_001088596
570
64876
P375
K
G
I
L
K
K
T
P
Q
R
E
S
G
Y
Y
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
A461
V
G
V
P
D
P
R
A
E
M
Q
E
D
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
T634
S
Y
K
P
S
S
N
T
T
Q
I
A
Q
I
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
R317
N
Q
V
L
E
S
L
R
N
R
T
Q
N
D
A
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
S423
T
F
Q
Q
Q
S
K
S
H
Q
K
S
Q
V
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.8
82
86.6
N.A.
85.4
85.7
N.A.
68.7
28.8
51.4
22.5
N.A.
N.A.
N.A.
22.1
N.A.
Protein Similarity:
100
65.9
84.5
90.1
N.A.
89.5
90.9
N.A.
75.8
43.4
64
33.4
N.A.
N.A.
N.A.
34.4
N.A.
P-Site Identity:
100
13.3
86.6
26.6
N.A.
66.6
60
N.A.
53.3
6.6
0
0
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
100
26.6
86.6
33.3
N.A.
73.3
66.6
N.A.
73.3
33.3
0
13.3
N.A.
N.A.
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.4
25.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.5
44.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
16
0
16
8
24
0
8
16
8
8
8
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
8
0
0
8
16
31
% D
% Glu:
0
0
0
0
8
0
0
0
16
16
24
16
0
39
16
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
16
0
8
0
0
0
0
0
24
24
0
16
8
8
% G
% His:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% H
% Ile:
8
0
16
0
0
0
0
0
0
0
8
0
0
8
0
% I
% Lys:
8
47
54
47
8
8
8
0
0
0
8
0
8
0
0
% K
% Leu:
47
0
0
16
0
8
16
0
0
0
0
0
8
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
8
8
0
8
0
0
0
8
0
0
% N
% Pro:
0
0
0
24
0
16
16
24
0
0
8
0
0
0
16
% P
% Gln:
0
8
8
8
8
0
0
0
8
16
8
16
47
0
8
% Q
% Arg:
0
16
0
0
0
0
8
8
8
24
0
8
0
0
0
% R
% Ser:
8
0
0
0
24
62
0
47
24
8
0
16
0
0
0
% S
% Thr:
8
0
8
0
8
0
31
8
8
0
8
8
0
0
0
% T
% Val:
8
0
16
0
24
0
0
8
0
0
0
24
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _