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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUAK2
All Species:
6.97
Human Site:
S430
Identified Species:
12.78
UniProt:
Q9H093
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H093
NP_112214.1
628
69612
S430
Q
E
D
P
P
E
L
S
P
I
P
A
S
P
G
Chimpanzee
Pan troglodytes
XP_001161041
661
74289
S455
A
E
V
P
G
K
L
S
P
K
Q
S
A
T
M
Rhesus Macaque
Macaca mulatta
XP_001088883
675
74111
S430
Q
G
D
L
Q
E
L
S
P
I
P
A
S
P
G
Dog
Lupus familis
XP_545687
631
69738
G434
G
D
P
E
P
G
P
G
P
M
D
P
G
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BZN4
639
70657
R442
Q
E
D
P
Q
E
L
R
P
V
P
D
T
P
G
Rat
Rattus norvegicus
Q66HE5
630
69934
R434
Q
E
G
P
Q
E
L
R
P
V
S
N
T
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515855
679
75174
A476
K
E
E
T
E
V
P
A
V
P
L
P
E
L
P
Chicken
Gallus gallus
Q9IA88
798
88848
F483
L
A
E
V
T
T
H
F
Y
Q
H
A
P
P
C
Frog
Xenopus laevis
NP_001088596
570
64876
H387
G
Y
Y
S
S
P
E
H
N
E
D
Q
T
Q
T
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
G473
D
L
Q
K
L
A
P
G
F
P
R
V
A
P
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
R646
Q
I
P
P
L
F
N
R
N
S
T
A
T
S
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
Y329
N
D
A
T
V
T
Y
Y
L
L
L
D
N
R
F
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
K435
Q
V
D
H
E
T
A
K
Q
H
A
R
R
M
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.8
82
86.6
N.A.
85.4
85.7
N.A.
68.7
28.8
51.4
22.5
N.A.
N.A.
N.A.
22.1
N.A.
Protein Similarity:
100
65.9
84.5
90.1
N.A.
89.5
90.9
N.A.
75.8
43.4
64
33.4
N.A.
N.A.
N.A.
34.4
N.A.
P-Site Identity:
100
33.3
80
13.3
N.A.
66.6
53.3
N.A.
6.6
13.3
0
6.6
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
100
53.3
80
26.6
N.A.
80
66.6
N.A.
26.6
20
6.6
13.3
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.4
25.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.5
44.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
0
0
8
8
8
0
0
8
31
16
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
8
16
31
0
0
0
0
0
0
0
16
16
0
0
0
% D
% Glu:
0
39
16
8
16
31
8
0
0
8
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
8
0
8
8
0
0
0
0
0
8
% F
% Gly:
16
8
8
0
8
8
0
16
0
0
0
0
8
0
31
% G
% His:
0
0
0
8
0
0
8
8
0
8
8
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
16
0
0
0
0
0
% I
% Lys:
8
0
0
8
0
8
0
8
0
8
0
0
0
0
0
% K
% Leu:
8
8
0
8
16
0
39
0
8
8
16
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
8
% M
% Asn:
8
0
0
0
0
0
8
0
16
0
0
8
8
0
0
% N
% Pro:
0
0
16
39
16
8
24
0
47
16
24
16
8
47
8
% P
% Gln:
47
0
8
0
24
0
0
0
8
8
8
8
0
16
8
% Q
% Arg:
0
0
0
0
0
0
0
24
0
0
8
8
8
8
0
% R
% Ser:
0
0
0
8
8
0
0
24
0
8
8
8
16
8
8
% S
% Thr:
0
0
0
16
8
24
0
0
0
0
8
0
31
8
8
% T
% Val:
0
8
8
8
8
8
0
0
8
16
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
8
0
0
0
8
8
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _