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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUAK2
All Species:
19.7
Human Site:
S480
Identified Species:
36.11
UniProt:
Q9H093
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H093
NP_112214.1
628
69612
S480
D
A
G
D
V
F
V
S
G
D
P
K
E
Q
K
Chimpanzee
Pan troglodytes
XP_001161041
661
74289
S499
D
S
N
D
V
M
G
S
S
I
P
S
P
S
P
Rhesus Macaque
Macaca mulatta
XP_001088883
675
74111
S480
D
A
G
D
V
F
V
S
G
D
P
K
E
Q
K
Dog
Lupus familis
XP_545687
631
69738
S482
D
A
G
D
V
F
M
S
A
D
S
E
E
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BZN4
639
70657
S495
D
A
S
D
V
F
V
S
G
D
P
V
E
Q
K
Rat
Rattus norvegicus
Q66HE5
630
69934
S487
D
A
G
D
V
F
V
S
G
D
P
M
E
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515855
679
75174
F530
D
A
D
A
G
D
V
F
S
S
S
P
S
P
Q
Chicken
Gallus gallus
Q9IA88
798
88848
L563
G
C
M
G
G
A
S
L
L
P
V
S
F
Q
E
Frog
Xenopus laevis
NP_001088596
570
64876
R430
E
P
A
P
N
A
G
R
K
G
I
L
K
R
N
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
K632
N
S
L
I
R
Q
L
K
Q
E
C
E
Q
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
S838
Q
S
P
S
M
P
P
S
Q
M
M
T
A
M
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
I372
A
S
P
V
G
H
W
I
P
A
H
V
D
H
Y
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
H478
P
T
S
L
P
Q
I
H
R
A
N
M
L
A
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.8
82
86.6
N.A.
85.4
85.7
N.A.
68.7
28.8
51.4
22.5
N.A.
N.A.
N.A.
22.1
N.A.
Protein Similarity:
100
65.9
84.5
90.1
N.A.
89.5
90.9
N.A.
75.8
43.4
64
33.4
N.A.
N.A.
N.A.
34.4
N.A.
P-Site Identity:
100
33.3
100
73.3
N.A.
86.6
93.3
N.A.
20
6.6
0
0
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
40
100
86.6
N.A.
86.6
93.3
N.A.
26.6
13.3
20
46.6
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.4
25.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.5
44.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
47
8
8
0
16
0
0
8
16
0
0
8
8
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
54
0
8
47
0
8
0
0
0
39
0
0
8
0
0
% D
% Glu:
8
0
0
0
0
0
0
0
0
8
0
16
39
0
16
% E
% Phe:
0
0
0
0
0
39
0
8
0
0
0
0
8
0
0
% F
% Gly:
8
0
31
8
24
0
16
0
31
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
8
0
8
0
0
8
0
0
8
0
% H
% Ile:
0
0
0
8
0
0
8
8
0
8
8
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
8
8
0
0
16
8
0
39
% K
% Leu:
0
0
8
8
0
0
8
8
8
0
0
8
8
8
0
% L
% Met:
0
0
8
0
8
8
8
0
0
8
8
16
0
8
0
% M
% Asn:
8
0
8
0
8
0
0
0
0
0
8
0
0
0
8
% N
% Pro:
8
8
16
8
8
8
8
0
8
8
39
8
8
8
8
% P
% Gln:
8
0
0
0
0
16
0
0
16
0
0
0
8
47
24
% Q
% Arg:
0
0
0
0
8
0
0
8
8
0
0
0
0
8
0
% R
% Ser:
0
31
16
8
0
0
8
54
16
8
16
16
8
8
0
% S
% Thr:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% T
% Val:
0
0
0
8
47
0
39
0
0
0
8
16
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _