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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUAK2
All Species:
21.52
Human Site:
S544
Identified Species:
39.44
UniProt:
Q9H093
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H093
NP_112214.1
628
69612
S544
S
R
P
S
G
A
V
S
E
D
S
I
L
S
S
Chimpanzee
Pan troglodytes
XP_001161041
661
74289
S573
S
R
P
S
S
V
I
S
D
D
S
V
L
S
S
Rhesus Macaque
Macaca mulatta
XP_001088883
675
74111
K544
S
R
P
S
G
A
V
K
I
P
F
T
L
V
L
Dog
Lupus familis
XP_545687
631
69738
S546
S
H
P
S
G
A
M
S
E
D
S
I
L
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BZN4
639
70657
S559
S
R
P
S
G
A
V
S
E
D
S
I
L
S
S
Rat
Rattus norvegicus
Q66HE5
630
69934
S550
S
R
P
S
G
A
V
S
E
D
S
I
L
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515855
679
75174
S595
S
R
P
S
S
A
I
S
E
D
S
I
L
S
T
Chicken
Gallus gallus
Q9IA88
798
88848
R645
Y
S
S
S
G
S
S
R
E
G
R
N
L
L
E
Frog
Xenopus laevis
NP_001088596
570
64876
D492
T
E
S
F
E
L
L
D
F
P
G
K
Y
R
E
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
P971
A
E
S
L
D
S
A
P
P
Q
A
T
P
T
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
H933
S
S
S
T
N
P
P
H
Q
H
Q
L
T
H
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
V434
Y
N
M
K
C
R
W
V
P
G
L
A
D
G
Q
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
L541
A
K
P
S
E
E
D
L
W
T
I
K
L
R
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.8
82
86.6
N.A.
85.4
85.7
N.A.
68.7
28.8
51.4
22.5
N.A.
N.A.
N.A.
22.1
N.A.
Protein Similarity:
100
65.9
84.5
90.1
N.A.
89.5
90.9
N.A.
75.8
43.4
64
33.4
N.A.
N.A.
N.A.
34.4
N.A.
P-Site Identity:
100
66.6
53.3
86.6
N.A.
100
100
N.A.
80
26.6
0
0
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
86.6
53.3
93.3
N.A.
100
100
N.A.
93.3
33.3
13.3
26.6
N.A.
N.A.
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.4
25.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.5
44.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
0
0
47
8
0
0
0
8
8
0
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
8
8
8
47
0
0
8
0
0
% D
% Glu:
0
16
0
0
16
8
0
0
47
0
0
0
0
0
16
% E
% Phe:
0
0
0
8
0
0
0
0
8
0
8
0
0
0
0
% F
% Gly:
0
0
0
0
47
0
0
0
0
16
8
0
0
8
0
% G
% His:
0
8
0
0
0
0
0
8
0
8
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
0
16
0
8
0
8
39
0
0
0
% I
% Lys:
0
8
0
8
0
0
0
8
0
0
0
16
0
0
0
% K
% Leu:
0
0
0
8
0
8
8
8
0
0
8
8
70
8
8
% L
% Met:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
8
0
0
0
0
0
0
8
0
0
8
% N
% Pro:
0
0
62
0
0
8
8
8
16
16
0
0
8
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
8
8
0
0
0
16
% Q
% Arg:
0
47
0
0
0
8
0
8
0
0
8
0
0
16
0
% R
% Ser:
62
16
31
70
16
16
8
47
0
0
47
0
0
47
39
% S
% Thr:
8
0
0
8
0
0
0
0
0
8
0
16
8
8
8
% T
% Val:
0
0
0
0
0
8
31
8
0
0
0
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
8
% W
% Tyr:
16
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _