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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NUAK2 All Species: 6.97
Human Site: S573 Identified Species: 12.78
UniProt: Q9H093 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H093 NP_112214.1 628 69612 S573 P P L R G C V S V D N L T G L
Chimpanzee Pan troglodytes XP_001161041 661 74289 N606 R S C V S A E N F L Q I Q D F
Rhesus Macaque Macaca mulatta XP_001088883 675 74111 S581 P P P P Y A N S L S P L Q S I
Dog Lupus familis XP_545687 631 69738 V576 V L R G C V S V D N L M G L E
Cat Felis silvestris
Mouse Mus musculus Q8BZN4 639 70657 R584 R L P E T P L R G C V S V D N
Rat Rattus norvegicus Q66HE5 630 69934 R575 R L P E T P L R G C V S V D N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515855 679 75174 S624 P A L R G C V S A D D L L G L
Chicken Gallus gallus Q9IA88 798 88848 A714 R E N S F E L A F G G N S Q L
Frog Xenopus laevis NP_001088596 570 64876 D516 R N S L S A E D L L Q L N E G
Zebra Danio Brachydanio rerio Q6NSM8 1187 130949 L1121 S L L A G K A L S S A R M S D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9TW45 1192 126331 S1108 W S M K T T S S L A P D D M M
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P92958 512 58671 I458 F R D E S S I I E D D C A M T
Baker's Yeast Sacchar. cerevisiae P06782 633 72027 M568 K I P D L M K M V I Q L F Q I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 53.8 82 86.6 N.A. 85.4 85.7 N.A. 68.7 28.8 51.4 22.5 N.A. N.A. N.A. 22.1 N.A.
Protein Similarity: 100 65.9 84.5 90.1 N.A. 89.5 90.9 N.A. 75.8 43.4 64 33.4 N.A. N.A. N.A. 34.4 N.A.
P-Site Identity: 100 0 26.6 0 N.A. 0 0 N.A. 73.3 6.6 6.6 13.3 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 13.3 40 13.3 N.A. 6.6 6.6 N.A. 80 26.6 13.3 13.3 N.A. N.A. N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 29.4 25.9 N.A.
Protein Similarity: N.A. N.A. N.A. 46.5 44.7 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 8 0 24 8 8 8 8 8 0 8 0 0 % A
% Cys: 0 0 8 0 8 16 0 0 0 16 0 8 0 0 0 % C
% Asp: 0 0 8 8 0 0 0 8 8 24 16 8 8 24 8 % D
% Glu: 0 8 0 24 0 8 16 0 8 0 0 0 0 8 8 % E
% Phe: 8 0 0 0 8 0 0 0 16 0 0 0 8 0 8 % F
% Gly: 0 0 0 8 24 0 0 0 16 8 8 0 8 16 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 0 8 8 0 8 0 8 0 0 16 % I
% Lys: 8 0 0 8 0 8 8 0 0 0 0 0 0 0 0 % K
% Leu: 0 31 24 8 8 0 24 8 24 16 8 39 8 8 24 % L
% Met: 0 0 8 0 0 8 0 8 0 0 0 8 8 16 8 % M
% Asn: 0 8 8 0 0 0 8 8 0 8 8 8 8 0 16 % N
% Pro: 24 16 31 8 0 16 0 0 0 0 16 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 24 0 16 16 0 % Q
% Arg: 39 8 8 16 0 0 0 16 0 0 0 8 0 0 0 % R
% Ser: 8 16 8 8 24 8 16 31 8 16 0 16 8 16 0 % S
% Thr: 0 0 0 0 24 8 0 0 0 0 0 0 8 0 8 % T
% Val: 8 0 0 8 0 8 16 8 16 0 16 0 16 0 0 % V
% Trp: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _