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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUAK2
All Species:
16.97
Human Site:
S606
Identified Species:
31.11
UniProt:
Q9H093
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H093
NP_112214.1
628
69612
S606
P
L
G
D
S
C
F
S
L
T
D
C
Q
E
V
Chimpanzee
Pan troglodytes
XP_001161041
661
74289
L639
L
A
D
S
S
F
S
L
L
T
D
M
D
D
V
Rhesus Macaque
Macaca mulatta
XP_001088883
675
74111
P614
R
E
G
E
D
K
V
P
A
S
S
R
L
A
L
Dog
Lupus familis
XP_545687
631
69738
S609
S
L
G
D
S
C
F
S
L
T
D
C
Q
E
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8BZN4
639
70657
S617
S
L
G
D
S
C
F
S
L
T
D
C
Q
E
V
Rat
Rattus norvegicus
Q66HE5
630
69934
S608
S
L
G
D
S
C
F
S
L
T
D
C
Q
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515855
679
75174
S657
P
L
R
D
S
C
F
S
L
T
D
C
Q
D
V
Chicken
Gallus gallus
Q9IA88
798
88848
I747
L
L
D
T
H
L
Y
I
S
S
N
V
S
P
V
Frog
Xenopus laevis
NP_001088596
570
64876
G549
A
E
S
C
L
S
L
G
A
G
E
E
E
V
L
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
D1154
P
V
C
D
V
D
A
D
V
H
S
S
S
C
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
H1141
R
Y
M
I
L
C
V
H
G
D
P
N
T
D
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
V491
Y
L
L
D
I
Q
R
V
N
G
P
Q
F
L
F
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
N601
G
D
D
T
T
V
S
N
I
S
E
D
E
M
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.8
82
86.6
N.A.
85.4
85.7
N.A.
68.7
28.8
51.4
22.5
N.A.
N.A.
N.A.
22.1
N.A.
Protein Similarity:
100
65.9
84.5
90.1
N.A.
89.5
90.9
N.A.
75.8
43.4
64
33.4
N.A.
N.A.
N.A.
34.4
N.A.
P-Site Identity:
100
33.3
6.6
93.3
N.A.
93.3
93.3
N.A.
86.6
13.3
0
13.3
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
40
26.6
93.3
N.A.
93.3
93.3
N.A.
93.3
33.3
20
26.6
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.4
25.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.5
44.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
8
0
16
0
0
0
0
8
0
% A
% Cys:
0
0
8
8
0
47
0
0
0
0
0
39
0
8
0
% C
% Asp:
0
8
24
54
8
8
0
8
0
8
47
8
8
24
0
% D
% Glu:
0
16
0
8
0
0
0
0
0
0
16
8
16
31
0
% E
% Phe:
0
0
0
0
0
8
39
0
0
0
0
0
8
0
8
% F
% Gly:
8
0
39
0
0
0
0
8
8
16
0
0
0
0
0
% G
% His:
0
0
0
0
8
0
0
8
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
8
8
0
0
8
8
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% K
% Leu:
16
54
8
0
16
8
8
8
47
0
0
0
8
8
16
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
8
0
8
0
% M
% Asn:
0
0
0
0
0
0
0
8
8
0
8
8
0
0
0
% N
% Pro:
24
0
0
0
0
0
0
8
0
0
16
0
0
8
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
8
39
0
0
% Q
% Arg:
16
0
8
0
0
0
8
0
0
0
0
8
0
0
0
% R
% Ser:
24
0
8
8
47
8
16
39
8
24
16
8
16
0
16
% S
% Thr:
0
0
0
16
8
0
0
0
0
47
0
0
8
0
0
% T
% Val:
0
8
0
0
8
8
16
8
8
0
0
8
0
8
54
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
0
0
8
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _