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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUAK2
All Species:
1.82
Human Site:
T578
Identified Species:
3.33
UniProt:
Q9H093
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H093
NP_112214.1
628
69612
T578
C
V
S
V
D
N
L
T
G
L
E
E
P
P
S
Chimpanzee
Pan troglodytes
XP_001161041
661
74289
Q611
A
E
N
F
L
Q
I
Q
D
F
E
G
L
Q
N
Rhesus Macaque
Macaca mulatta
XP_001088883
675
74111
Q586
A
N
S
L
S
P
L
Q
S
I
P
H
T
P
A
Dog
Lupus familis
XP_545687
631
69738
G581
V
S
V
D
N
L
M
G
L
E
E
P
P
A
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BZN4
639
70657
V589
P
L
R
G
C
V
S
V
D
N
L
R
G
L
E
Rat
Rattus norvegicus
Q66HE5
630
69934
V580
P
L
R
G
C
V
S
V
D
N
L
R
R
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515855
679
75174
L629
C
V
S
A
D
D
L
L
G
L
E
E
E
E
E
Chicken
Gallus gallus
Q9IA88
798
88848
S719
E
L
A
F
G
G
N
S
Q
L
L
Q
P
H
F
Frog
Xenopus laevis
NP_001088596
570
64876
N521
A
E
D
L
L
Q
L
N
E
G
N
K
Q
D
I
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
M1126
K
A
L
S
S
A
R
M
S
D
I
L
S
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
D1113
T
S
S
L
A
P
D
D
M
M
R
E
I
R
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
A463
S
I
I
E
D
D
C
A
M
T
S
P
T
V
I
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
F573
M
K
M
V
I
Q
L
F
Q
I
E
T
N
N
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.8
82
86.6
N.A.
85.4
85.7
N.A.
68.7
28.8
51.4
22.5
N.A.
N.A.
N.A.
22.1
N.A.
Protein Similarity:
100
65.9
84.5
90.1
N.A.
89.5
90.9
N.A.
75.8
43.4
64
33.4
N.A.
N.A.
N.A.
34.4
N.A.
P-Site Identity:
100
6.6
20
13.3
N.A.
0
0
N.A.
60
13.3
6.6
6.6
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
26.6
40
26.6
N.A.
6.6
6.6
N.A.
66.6
40
20
6.6
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.4
25.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.5
44.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
8
8
8
8
8
0
8
0
0
0
0
0
8
8
% A
% Cys:
16
0
0
0
16
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
24
16
8
8
24
8
0
0
0
8
0
% D
% Glu:
8
16
0
8
0
0
0
0
8
8
39
24
8
8
31
% E
% Phe:
0
0
0
16
0
0
0
8
0
8
0
0
0
0
8
% F
% Gly:
0
0
0
16
8
8
0
8
16
8
0
8
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% H
% Ile:
0
8
8
0
8
0
8
0
0
16
8
0
8
0
16
% I
% Lys:
8
8
0
0
0
0
0
0
0
0
0
8
0
0
8
% K
% Leu:
0
24
8
24
16
8
39
8
8
24
24
8
8
16
0
% L
% Met:
8
0
8
0
0
0
8
8
16
8
0
0
0
0
0
% M
% Asn:
0
8
8
0
8
8
8
8
0
16
8
0
8
8
8
% N
% Pro:
16
0
0
0
0
16
0
0
0
0
8
16
24
16
0
% P
% Gln:
0
0
0
0
0
24
0
16
16
0
0
8
8
16
0
% Q
% Arg:
0
0
16
0
0
0
8
0
0
0
8
16
8
8
0
% R
% Ser:
8
16
31
8
16
0
16
8
16
0
8
0
8
0
16
% S
% Thr:
8
0
0
0
0
0
0
8
0
8
0
8
16
0
0
% T
% Val:
8
16
8
16
0
16
0
16
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _