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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IQCG All Species: 11.52
Human Site: Y247 Identified Species: 28.15
UniProt: Q9H095 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H095 NP_001127907.1 443 51918 Y247 E V Q S Q N E Y I A N L K D Q
Chimpanzee Pan troglodytes XP_516986 95 10588
Rhesus Macaque Macaca mulatta XP_001103600 443 51713 Y247 E V Q S Q N E Y I A N L K D Q
Dog Lupus familis XP_849296 444 52179 Y247 E I Q S R N E Y I A H L K D Q
Cat Felis silvestris
Mouse Mus musculus Q80W32 419 49150 L234 I A H L R D Q L Q E M K A K T
Rat Rattus norvegicus Q5PQQ6 419 48738 Q234 A H L R D Q L Q E V K A K T N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516729 656 72730 H407 K V Q S Q K E H I A Y L K D Q
Chicken Gallus gallus XP_422733 396 46036 Y220 K A A M E Q R Y M K K S A D L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651566 448 53047 R265 K L Q D L E E R I A D T K Y K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785186 190 22620 S14 Q E M K A K T S M E G K Y V Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 20.9 90.5 72.7 N.A. 63.8 62.7 N.A. 38.1 37 N.A. N.A. N.A. 21.4 N.A. N.A. 24.3
Protein Similarity: 100 21.4 95.9 84.9 N.A. 79.4 79 N.A. 51.3 58.9 N.A. N.A. N.A. 44.2 N.A. N.A. 33.6
P-Site Identity: 100 0 100 80 N.A. 0 6.6 N.A. 73.3 13.3 N.A. N.A. N.A. 33.3 N.A. N.A. 6.6
P-Site Similarity: 100 0 100 100 N.A. 20 6.6 N.A. 86.6 33.3 N.A. N.A. N.A. 60 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 20 10 0 10 0 0 0 0 50 0 10 20 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 10 10 0 0 0 0 10 0 0 50 0 % D
% Glu: 30 10 0 0 10 10 50 0 10 20 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % G
% His: 0 10 10 0 0 0 0 10 0 0 10 0 0 0 0 % H
% Ile: 10 10 0 0 0 0 0 0 50 0 0 0 0 0 0 % I
% Lys: 30 0 0 10 0 20 0 0 0 10 20 20 60 10 10 % K
% Leu: 0 10 10 10 10 0 10 10 0 0 0 40 0 0 10 % L
% Met: 0 0 10 10 0 0 0 0 20 0 10 0 0 0 0 % M
% Asn: 0 0 0 0 0 30 0 0 0 0 20 0 0 0 10 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 10 0 50 0 30 20 10 10 10 0 0 0 0 0 50 % Q
% Arg: 0 0 0 10 20 0 10 10 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 40 0 0 0 10 0 0 0 10 0 0 0 % S
% Thr: 0 0 0 0 0 0 10 0 0 0 0 10 0 10 10 % T
% Val: 0 30 0 0 0 0 0 0 0 10 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 40 0 0 10 0 10 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _