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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COMMD4
All Species:
21.52
Human Site:
S115
Identified Species:
39.44
UniProt:
Q9H0A8
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H0A8
NP_060298.2
199
21764
S115
R
C
Y
E
E
K
Q
S
P
L
Q
K
H
L
R
Chimpanzee
Pan troglodytes
XP_510680
409
44350
S325
R
C
Y
E
E
K
Q
S
P
L
Q
K
H
L
R
Rhesus Macaque
Macaca mulatta
XP_001101270
200
21927
A114
S
F
I
L
S
S
A
A
K
H
S
V
D
G
E
Dog
Lupus familis
XP_853327
199
21783
S115
R
C
Y
E
E
K
Q
S
P
L
Q
E
H
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQ02
199
21842
S115
R
C
Y
E
E
K
Q
S
P
L
Q
E
H
L
R
Rat
Rattus norvegicus
NP_001102232
177
19467
H98
K
Q
S
P
L
Q
E
H
L
R
A
C
S
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518553
198
21716
S114
R
S
Y
E
E
K
Q
S
P
L
Q
D
S
L
R
Chicken
Gallus gallus
XP_001233363
199
22075
S115
R
S
Y
E
E
K
Q
S
S
L
Q
D
S
L
R
Frog
Xenopus laevis
NP_001089048
197
22070
N115
R
S
Y
E
E
K
Q
N
A
L
Q
E
T
L
R
Zebra Danio
Brachydanio rerio
NP_001070206
134
15049
T55
Y
D
K
V
S
K
L
T
S
D
A
K
F
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001034012
198
22035
A113
R
V
L
Q
K
H
S
A
T
I
R
Q
T
L
I
Honey Bee
Apis mellifera
XP_393404
188
20764
A105
L
P
R
E
H
S
A
A
I
A
R
L
H
T
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785030
205
23099
E121
R
S
Y
G
D
K
R
E
K
M
Q
E
S
F
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
48.4
69
93.9
N.A.
90.9
79.4
N.A.
81.4
72.8
65.3
49.2
N.A.
34.6
40.7
N.A.
56.5
Protein Similarity:
100
48.6
72.5
97.9
N.A.
95.9
84.4
N.A.
89.9
82.9
83.9
59.2
N.A.
55.2
62.3
N.A.
75.6
P-Site Identity:
100
100
0
93.3
N.A.
93.3
13.3
N.A.
80
73.3
66.6
13.3
N.A.
13.3
13.3
N.A.
33.3
P-Site Similarity:
100
100
6.6
100
N.A.
100
33.3
N.A.
80
73.3
80
20
N.A.
53.3
26.6
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
16
24
8
8
16
0
0
0
0
% A
% Cys:
0
31
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
8
0
0
8
0
0
0
0
8
0
16
8
8
8
% D
% Glu:
0
0
0
62
54
0
8
8
0
0
0
31
0
0
8
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
8
8
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
8
8
0
8
0
8
0
0
39
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
8
8
0
0
0
0
8
% I
% Lys:
8
0
8
0
8
70
0
0
16
0
0
24
0
0
0
% K
% Leu:
8
0
8
8
8
0
8
0
8
54
0
8
0
70
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
8
0
0
0
0
39
0
0
0
0
0
0
% P
% Gln:
0
8
0
8
0
8
54
0
0
0
62
8
0
0
0
% Q
% Arg:
70
0
8
0
0
0
8
0
0
8
16
0
0
0
70
% R
% Ser:
8
31
8
0
16
16
8
47
16
0
8
0
31
0
8
% S
% Thr:
0
0
0
0
0
0
0
8
8
0
0
0
16
8
0
% T
% Val:
0
8
0
8
0
0
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
62
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _