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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COMMD4
All Species:
31.82
Human Site:
S88
Identified Species:
58.33
UniProt:
Q9H0A8
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H0A8
NP_060298.2
199
21764
S88
K
H
S
V
D
G
E
S
L
S
S
E
L
Q
Q
Chimpanzee
Pan troglodytes
XP_510680
409
44350
S298
K
H
S
V
D
G
E
S
L
S
S
E
L
Q
Q
Rhesus Macaque
Macaca mulatta
XP_001101270
200
21927
K87
I
D
Y
E
K
I
L
K
L
T
A
D
T
K
F
Dog
Lupus familis
XP_853327
199
21783
S88
K
H
S
V
D
G
E
S
L
S
S
E
L
Q
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQ02
199
21842
S88
K
H
S
V
D
S
D
S
L
S
S
E
L
Q
Q
Rat
Rattus norvegicus
NP_001102232
177
19467
L71
S
D
S
L
S
S
E
L
Q
Q
L
G
L
P
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518553
198
21716
S87
K
H
N
V
D
G
E
S
L
S
S
E
L
Q
Q
Chicken
Gallus gallus
XP_001233363
199
22075
S88
K
H
N
V
D
G
E
S
L
S
S
E
L
Q
Q
Frog
Xenopus laevis
NP_001089048
197
22070
S88
K
H
N
V
S
S
D
S
L
S
S
E
L
Q
Q
Zebra Danio
Brachydanio rerio
NP_001070206
134
15049
V28
T
L
A
R
I
S
S
V
K
M
K
L
L
C
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001034012
198
22035
I86
R
Y
S
C
S
E
S
I
F
G
E
E
I
Q
Q
Honey Bee
Apis mellifera
XP_393404
188
20764
S78
A
L
E
L
I
F
T
S
S
A
R
Y
G
V
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785030
205
23099
S94
K
Y
N
V
D
G
E
S
L
S
N
E
L
Q
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
48.4
69
93.9
N.A.
90.9
79.4
N.A.
81.4
72.8
65.3
49.2
N.A.
34.6
40.7
N.A.
56.5
Protein Similarity:
100
48.6
72.5
97.9
N.A.
95.9
84.4
N.A.
89.9
82.9
83.9
59.2
N.A.
55.2
62.3
N.A.
75.6
P-Site Identity:
100
100
6.6
100
N.A.
86.6
20
N.A.
93.3
93.3
73.3
6.6
N.A.
26.6
6.6
N.A.
80
P-Site Similarity:
100
100
33.3
100
N.A.
93.3
33.3
N.A.
100
100
86.6
13.3
N.A.
46.6
20
N.A.
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
0
0
0
0
8
8
0
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
16
0
0
54
0
16
0
0
0
0
8
0
0
0
% D
% Glu:
0
0
8
8
0
8
54
0
0
0
8
70
0
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
47
0
0
0
8
0
8
8
0
0
% G
% His:
0
54
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
16
8
0
8
0
0
0
0
8
0
0
% I
% Lys:
62
0
0
0
8
0
0
8
8
0
8
0
0
8
8
% K
% Leu:
0
16
0
16
0
0
8
8
70
0
8
8
77
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
31
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
8
0
0
0
70
70
% Q
% Arg:
8
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
8
0
47
0
24
31
16
70
8
62
54
0
0
0
8
% S
% Thr:
8
0
0
0
0
0
8
0
0
8
0
0
8
0
0
% T
% Val:
0
0
0
62
0
0
0
8
0
0
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
16
8
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _