KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLC2
All Species:
22.73
Human Site:
S175
Identified Species:
45.45
UniProt:
Q9H0B6
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H0B6
NP_001128246.1
622
68935
S175
F
P
N
E
D
E
Q
S
P
A
P
S
P
G
G
Chimpanzee
Pan troglodytes
XP_522069
622
68914
S175
F
P
N
E
D
E
Q
S
P
A
P
S
P
G
G
Rhesus Macaque
Macaca mulatta
XP_001111092
622
68682
S175
F
P
N
E
D
E
Q
S
P
A
P
S
P
G
G
Dog
Lupus familis
XP_540836
602
66612
S175
F
P
N
E
E
E
Q
S
P
A
P
S
P
G
G
Cat
Felis silvestris
Mouse
Mus musculus
O88448
599
66644
S174
F
P
N
E
D
E
Q
S
P
A
P
S
P
G
G
Rat
Rattus norvegicus
Q5PQM2
619
68945
S188
N
E
E
E
E
D
S
S
N
D
L
S
R
G
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508875
610
68899
E149
E
E
E
K
K
H
L
E
F
M
N
Q
L
K
K
Chicken
Gallus gallus
XP_001233279
630
70872
G186
E
E
E
E
H
G
P
G
L
P
H
Q
H
S
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001077019
618
68858
D174
D
L
F
P
N
D
D
D
Q
G
P
A
Q
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P46824
508
58026
R86
H
K
L
K
T
Q
V
R
R
L
H
Q
E
N
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P46822
540
60206
S118
T
Q
I
K
L
Q
Q
S
E
Q
M
V
A
Q
L
Sea Urchin
Strong. purpuratus
Q05090
686
76498
Y192
G
G
Q
A
D
E
S
Y
P
Q
P
Q
T
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.5
91
N.A.
90.1
70.4
N.A.
68
72.3
N.A.
79.5
N.A.
55.4
N.A.
52.2
57.8
Protein Similarity:
100
99.8
98.8
92.9
N.A.
93
80.7
N.A.
79.2
81.7
N.A.
88.2
N.A.
67.8
N.A.
65.7
69.8
P-Site Identity:
100
100
100
93.3
N.A.
100
26.6
N.A.
0
6.6
N.A.
6.6
N.A.
0
N.A.
13.3
33.3
P-Site Similarity:
100
100
100
100
N.A.
100
40
N.A.
6.6
6.6
N.A.
26.6
N.A.
13.3
N.A.
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
0
0
42
0
9
9
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
42
17
9
9
0
9
0
0
0
0
0
% D
% Glu:
17
25
25
59
17
50
0
9
9
0
0
0
9
0
0
% E
% Phe:
42
0
9
0
0
0
0
0
9
0
0
0
0
0
0
% F
% Gly:
9
9
0
0
0
9
0
9
0
9
0
0
0
59
42
% G
% His:
9
0
0
0
9
9
0
0
0
0
17
0
9
0
0
% H
% Ile:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
9
0
25
9
0
0
0
0
0
0
0
0
9
9
% K
% Leu:
0
9
9
0
9
0
9
0
9
9
9
0
9
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% M
% Asn:
9
0
42
0
9
0
0
0
9
0
9
0
0
9
0
% N
% Pro:
0
42
0
9
0
0
9
0
50
9
59
0
42
9
0
% P
% Gln:
0
9
9
0
0
17
50
0
9
17
0
34
9
9
9
% Q
% Arg:
0
0
0
0
0
0
0
9
9
0
0
0
9
0
0
% R
% Ser:
0
0
0
0
0
0
17
59
0
0
0
50
0
9
25
% S
% Thr:
9
0
0
0
9
0
0
0
0
0
0
0
9
0
0
% T
% Val:
0
0
0
0
0
0
9
0
0
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _