KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLC2
All Species:
15.45
Human Site:
S537
Identified Species:
30.91
UniProt:
Q9H0B6
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H0B6
NP_001128246.1
622
68935
S537
A
E
W
N
G
D
G
S
G
S
L
R
R
S
G
Chimpanzee
Pan troglodytes
XP_522069
622
68914
S537
A
E
W
N
G
D
G
S
G
S
L
R
R
S
G
Rhesus Macaque
Macaca mulatta
XP_001111092
622
68682
S537
A
E
W
S
G
D
G
S
G
S
L
R
R
S
G
Dog
Lupus familis
XP_540836
602
66612
S517
A
E
W
S
G
D
G
S
G
S
L
R
R
S
G
Cat
Felis silvestris
Mouse
Mus musculus
O88448
599
66644
E514
D
V
A
G
P
Q
S
E
S
D
L
E
E
S
G
Rat
Rattus norvegicus
Q5PQM2
619
68945
E533
S
V
K
F
E
G
G
E
D
A
S
V
A
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508875
610
68899
E514
A
E
V
L
N
D
P
E
S
I
E
K
R
R
S
Chicken
Gallus gallus
XP_001233279
630
70872
L546
S
G
D
G
S
G
T
L
Q
R
S
S
S
L
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001077019
618
68858
N533
A
E
W
S
G
D
G
N
G
G
L
R
R
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P46824
508
58026
G424
T
P
Y
G
E
Y
G
G
W
H
K
A
A
K
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P46822
540
60206
T456
K
V
D
S
P
T
V
T
T
T
L
K
N
L
G
Sea Urchin
Strong. purpuratus
Q05090
686
76498
G560
V
S
Y
E
K
T
D
G
S
E
E
V
S
I
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.5
91
N.A.
90.1
70.4
N.A.
68
72.3
N.A.
79.5
N.A.
55.4
N.A.
52.2
57.8
Protein Similarity:
100
99.8
98.8
92.9
N.A.
93
80.7
N.A.
79.2
81.7
N.A.
88.2
N.A.
67.8
N.A.
65.7
69.8
P-Site Identity:
100
100
93.3
93.3
N.A.
20
6.6
N.A.
26.6
6.6
N.A.
80
N.A.
6.6
N.A.
13.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
20
20
N.A.
33.3
13.3
N.A.
93.3
N.A.
13.3
N.A.
40
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
0
9
0
0
0
0
0
0
9
0
9
17
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
17
0
0
50
9
0
9
9
0
0
0
0
0
% D
% Glu:
0
50
0
9
17
0
0
25
0
9
17
9
9
0
9
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
25
42
17
59
17
42
9
0
0
0
0
75
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
9
0
0
0
9
0
% I
% Lys:
9
0
9
0
9
0
0
0
0
0
9
17
0
9
0
% K
% Leu:
0
0
0
9
0
0
0
9
0
0
59
0
0
17
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
17
9
0
0
9
0
0
0
0
9
0
0
% N
% Pro:
0
9
0
0
17
0
9
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
9
0
0
9
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
9
0
42
50
9
0
% R
% Ser:
17
9
0
34
9
0
9
34
25
34
17
9
17
50
9
% S
% Thr:
9
0
0
0
0
17
9
9
9
9
0
0
0
0
0
% T
% Val:
9
25
9
0
0
0
9
0
0
0
0
17
0
9
9
% V
% Trp:
0
0
42
0
0
0
0
0
9
0
0
0
0
0
0
% W
% Tyr:
0
0
17
0
0
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _