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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KLC2 All Species: 19.09
Human Site: S543 Identified Species: 38.18
UniProt: Q9H0B6 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H0B6 NP_001128246.1 622 68935 S543 G S G S L R R S G S F G K L R
Chimpanzee Pan troglodytes XP_522069 622 68914 S543 G S G S L R R S G S F G K L R
Rhesus Macaque Macaca mulatta XP_001111092 622 68682 S543 G S G S L R R S G S F G K L R
Dog Lupus familis XP_540836 602 66612 S523 G S G S L R R S G S F G K L R
Cat Felis silvestris
Mouse Mus musculus O88448 599 66644 S520 S E S D L E E S G P A A E W S
Rat Rattus norvegicus Q5PQM2 619 68945 V539 G E D A S V A V E W S G D G S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508875 610 68899 R520 P E S I E K R R S R E S L N V
Chicken Gallus gallus XP_001233279 630 70872 L552 T L Q R S S S L G K I R E V I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001077019 618 68858 S539 G N G G L R R S G S F G K I R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46824 508 58026 K430 G G W H K A A K V D S P T V T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P46822 540 60206 L462 V T T T L K N L G A L Y R R Q
Sea Urchin Strong. purpuratus Q05090 686 76498 I566 D G S E E V S I G V A W K A K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98.5 91 N.A. 90.1 70.4 N.A. 68 72.3 N.A. 79.5 N.A. 55.4 N.A. 52.2 57.8
Protein Similarity: 100 99.8 98.8 92.9 N.A. 93 80.7 N.A. 79.2 81.7 N.A. 88.2 N.A. 67.8 N.A. 65.7 69.8
P-Site Identity: 100 100 100 100 N.A. 20 13.3 N.A. 6.6 6.6 N.A. 80 N.A. 6.6 N.A. 13.3 13.3
P-Site Similarity: 100 100 100 100 N.A. 26.6 20 N.A. 13.3 20 N.A. 93.3 N.A. 13.3 N.A. 53.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 9 17 0 0 9 17 9 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 9 9 0 0 0 0 0 9 0 0 9 0 0 % D
% Glu: 0 25 0 9 17 9 9 0 9 0 9 0 17 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 42 0 0 0 0 % F
% Gly: 59 17 42 9 0 0 0 0 75 0 0 50 0 9 0 % G
% His: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 9 0 0 0 9 0 0 9 0 0 9 9 % I
% Lys: 0 0 0 0 9 17 0 9 0 9 0 0 50 0 9 % K
% Leu: 0 9 0 0 59 0 0 17 0 0 9 0 9 34 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 0 0 0 9 0 0 0 0 0 0 9 0 % N
% Pro: 9 0 0 0 0 0 0 0 0 9 0 9 0 0 0 % P
% Gln: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 9 % Q
% Arg: 0 0 0 9 0 42 50 9 0 9 0 9 9 9 42 % R
% Ser: 9 34 25 34 17 9 17 50 9 42 17 9 0 0 17 % S
% Thr: 9 9 9 9 0 0 0 0 0 0 0 0 9 0 9 % T
% Val: 9 0 0 0 0 17 0 9 9 9 0 0 0 17 9 % V
% Trp: 0 0 9 0 0 0 0 0 0 9 0 9 0 9 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _