KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZMYND12
All Species:
12.12
Human Site:
Y252
Identified Species:
38.1
UniProt:
Q9H0C1
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H0C1
NP_001139664.1
365
41784
Y252
H
A
Y
L
N
N
H
Y
Q
V
L
S
Q
A
H
Chimpanzee
Pan troglodytes
XP_513364
365
41737
Y252
H
A
Y
L
N
N
H
Y
Q
V
L
S
Q
A
H
Rhesus Macaque
Macaca mulatta
XP_001086575
365
41750
Y252
H
A
Y
L
N
N
H
Y
Q
V
L
S
Q
A
H
Dog
Lupus familis
XP_539561
366
41872
Y252
S
K
Y
L
N
N
R
Y
Q
V
L
S
Q
N
R
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
NP_001101440
298
32984
L189
Y
S
L
K
K
M
E
L
A
D
T
L
Y
T
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505607
371
42472
I255
R
K
H
L
D
K
L
I
Q
F
Q
L
D
S
I
Chicken
Gallus gallus
XP_417661
365
40404
V253
H
T
F
L
V
K
S
V
Q
T
Q
E
Q
I
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794557
378
42714
V252
H
T
H
L
L
R
L
V
R
A
R
T
H
R
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
97.8
86
N.A.
N.A.
59.7
N.A.
51.7
47.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
45.5
Protein Similarity:
100
99.7
98.3
92.3
N.A.
N.A.
67.1
N.A.
70
64.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
65.3
P-Site Identity:
100
100
100
66.6
N.A.
N.A.
0
N.A.
13.3
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
66.6
N.A.
N.A.
13.3
N.A.
33.3
40
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
38
0
0
0
0
0
0
13
13
0
0
0
38
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
13
0
0
0
0
13
0
0
13
0
0
% D
% Glu:
0
0
0
0
0
0
13
0
0
0
0
13
0
0
0
% E
% Phe:
0
0
13
0
0
0
0
0
0
13
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
63
0
25
0
0
0
38
0
0
0
0
0
13
0
50
% H
% Ile:
0
0
0
0
0
0
0
13
0
0
0
0
0
13
13
% I
% Lys:
0
25
0
13
13
25
0
0
0
0
0
0
0
0
13
% K
% Leu:
0
0
13
88
13
0
25
13
0
0
50
25
0
0
0
% L
% Met:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
50
50
0
0
0
0
0
0
0
13
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
75
0
25
0
63
0
0
% Q
% Arg:
13
0
0
0
0
13
13
0
13
0
13
0
0
13
13
% R
% Ser:
13
13
0
0
0
0
13
0
0
0
0
50
0
13
0
% S
% Thr:
0
25
0
0
0
0
0
0
0
13
13
13
0
13
0
% T
% Val:
0
0
0
0
13
0
0
25
0
50
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
13
0
50
0
0
0
0
50
0
0
0
0
13
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _