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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC25A31
All Species:
40.91
Human Site:
S254
Identified Species:
60
UniProt:
Q9H0C2
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H0C2
NP_112581.1
315
35022
S254
R
R
R
M
M
M
Q
S
G
E
A
K
R
Q
Y
Chimpanzee
Pan troglodytes
XP_001156886
315
34984
S254
R
R
R
M
M
M
Q
S
G
E
A
K
R
Q
Y
Rhesus Macaque
Macaca mulatta
XP_001105150
315
35056
S254
R
R
R
M
M
M
Q
S
G
E
A
K
R
Q
Y
Dog
Lupus familis
XP_540952
459
49686
S394
R
R
R
M
M
M
Q
S
G
E
V
E
R
Q
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q3V132
320
35239
S255
R
R
R
M
M
M
Q
S
G
E
S
D
R
Q
Y
Rat
Rattus norvegicus
Q05962
298
32971
S242
R
R
R
M
M
M
Q
S
G
R
K
G
A
D
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006443
298
32950
S242
R
R
R
M
M
M
Q
S
G
R
K
G
A
D
I
Frog
Xenopus laevis
Q7T0U6
473
52371
R411
P
L
A
L
I
R
T
R
M
Q
A
Q
A
S
I
Zebra Danio
Brachydanio rerio
Q66L49
477
53337
R413
P
L
A
L
I
R
T
R
M
Q
A
M
A
S
M
Tiger Blowfish
Takifugu rubipres
NP_001037839
298
32885
S242
R
R
R
M
M
M
Q
S
G
R
K
G
A
D
I
Fruit Fly
Dros. melanogaster
Q26365
312
34196
S256
R
R
R
M
M
M
Q
S
G
R
K
A
T
E
V
Honey Bee
Apis mellifera
NP_001010975
300
32968
S244
R
R
R
M
M
M
Q
S
G
R
A
K
S
E
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P04709
387
42373
T323
V
R
R
R
M
M
M
T
S
G
E
A
V
K
Y
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P40941
385
41727
T321
V
R
R
R
M
M
M
T
S
G
E
A
V
K
Y
Baker's Yeast
Sacchar. cerevisiae
P18238
307
33294
T247
V
R
R
R
M
M
M
T
S
G
Q
A
V
K
Y
Red Bread Mold
Neurospora crassa
P02723
313
33870
T249
I
R
R
R
M
M
M
T
S
G
E
A
V
K
Y
Conservation
Percent
Protein Identity:
100
99.6
99.3
63.6
N.A.
87.5
68.2
N.A.
N.A.
68.5
23
22.2
67.6
69.2
70.1
N.A.
N.A.
Protein Similarity:
100
99.6
99.6
67
N.A.
93.7
79.6
N.A.
N.A.
80.3
37
36.2
80.3
80.6
81.5
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
86.6
60
N.A.
N.A.
60
6.6
6.6
60
60
73.3
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
60
N.A.
N.A.
60
33.3
26.6
60
66.6
80
N.A.
N.A.
Percent
Protein Identity:
N.A.
44.4
N.A.
45.7
52
53.3
Protein Similarity:
N.A.
56.8
N.A.
55
65.4
65.4
P-Site Identity:
N.A.
33.3
N.A.
33.3
33.3
33.3
P-Site Similarity:
N.A.
46.6
N.A.
46.6
46.6
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
13
0
0
0
0
0
0
0
38
32
32
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
7
0
19
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
32
19
7
0
13
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
63
25
0
19
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
0
13
0
0
0
0
0
0
0
0
0
32
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
25
25
0
25
0
% K
% Leu:
0
13
0
13
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
63
88
88
25
0
13
0
0
7
0
0
7
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
63
0
0
13
7
7
0
32
0
% Q
% Arg:
63
88
88
25
0
13
0
13
0
32
0
0
32
0
0
% R
% Ser:
0
0
0
0
0
0
0
63
25
0
7
0
7
13
0
% S
% Thr:
0
0
0
0
0
0
13
25
0
0
0
0
7
0
0
% T
% Val:
19
0
0
0
0
0
0
0
0
0
7
0
25
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
57
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _