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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC25A31
All Species:
35.45
Human Site:
S54
Identified Species:
52
UniProt:
Q9H0C2
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H0C2
NP_112581.1
315
35022
S54
L
L
Q
V
Q
A
S
S
K
Q
I
S
P
E
A
Chimpanzee
Pan troglodytes
XP_001156886
315
34984
S54
L
L
Q
V
Q
A
S
S
K
Q
I
S
P
E
A
Rhesus Macaque
Macaca mulatta
XP_001105150
315
35056
S54
L
L
Q
V
Q
A
S
S
K
Q
I
S
P
E
A
Dog
Lupus familis
XP_540952
459
49686
S194
L
L
Q
V
Q
A
S
S
K
Q
I
S
A
E
T
Cat
Felis silvestris
Mouse
Mus musculus
Q3V132
320
35239
S55
L
L
Q
V
Q
A
S
S
K
Q
I
S
P
E
A
Rat
Rattus norvegicus
Q05962
298
32971
S42
L
L
Q
V
Q
H
A
S
K
Q
I
S
A
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006443
298
32950
S42
L
L
Q
V
Q
H
A
S
K
Q
I
T
A
E
K
Frog
Xenopus laevis
Q7T0U6
473
52371
E186
T
I
P
D
E
F
T
E
E
E
K
K
T
G
Q
Zebra Danio
Brachydanio rerio
Q66L49
477
53337
E187
T
I
P
D
E
F
T
E
E
E
K
T
T
G
M
Tiger Blowfish
Takifugu rubipres
NP_001037839
298
32885
S42
L
L
Q
V
Q
H
A
S
K
Q
I
A
V
D
Q
Fruit Fly
Dros. melanogaster
Q26365
312
34196
S57
L
L
Q
V
Q
H
I
S
K
Q
I
S
P
D
K
Honey Bee
Apis mellifera
NP_001010975
300
32968
S44
L
L
Q
V
Q
H
I
S
K
Q
I
S
E
E
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P04709
387
42373
I122
I
Q
N
Q
D
E
M
I
K
S
G
R
L
S
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P40941
385
41727
L119
I
Q
N
Q
D
E
M
L
K
A
G
R
L
T
E
Baker's Yeast
Sacchar. cerevisiae
P18238
307
33294
I47
I
Q
N
Q
D
E
M
I
K
Q
G
T
L
D
K
Red Bread Mold
Neurospora crassa
P02723
313
33870
I48
V
Q
N
Q
D
E
M
I
R
A
G
R
L
D
R
Conservation
Percent
Protein Identity:
100
99.6
99.3
63.6
N.A.
87.5
68.2
N.A.
N.A.
68.5
23
22.2
67.6
69.2
70.1
N.A.
N.A.
Protein Similarity:
100
99.6
99.6
67
N.A.
93.7
79.6
N.A.
N.A.
80.3
37
36.2
80.3
80.6
81.5
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
100
73.3
N.A.
N.A.
66.6
0
0
60
73.3
73.3
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
100
80
N.A.
N.A.
80
33.3
40
80
80
73.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
44.4
N.A.
45.7
52
53.3
Protein Similarity:
N.A.
56.8
N.A.
55
65.4
65.4
P-Site Identity:
N.A.
6.6
N.A.
6.6
13.3
0
P-Site Similarity:
N.A.
13.3
N.A.
13.3
33.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
32
19
0
0
13
0
7
19
0
25
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
13
25
0
0
0
0
0
0
0
0
25
0
% D
% Glu:
0
0
0
0
13
25
0
13
13
13
0
0
7
50
13
% E
% Phe:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
25
0
0
13
0
% G
% His:
0
0
0
0
0
32
0
0
0
0
0
0
0
0
0
% H
% Ile:
19
13
0
0
0
0
13
19
0
0
63
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
82
0
13
7
0
0
25
% K
% Leu:
63
63
0
0
0
0
0
7
0
0
0
0
25
0
0
% L
% Met:
0
0
0
0
0
0
25
0
0
0
0
0
0
0
7
% M
% Asn:
0
0
25
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
13
0
0
0
0
0
0
0
0
0
32
0
0
% P
% Gln:
0
25
63
25
63
0
0
0
0
69
0
0
0
0
19
% Q
% Arg:
0
0
0
0
0
0
0
0
7
0
0
19
0
0
7
% R
% Ser:
0
0
0
0
0
0
32
63
0
7
0
50
0
7
0
% S
% Thr:
13
0
0
0
0
0
13
0
0
0
0
19
13
7
7
% T
% Val:
7
0
0
63
0
0
0
0
0
0
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _