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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC25A31 All Species: 19.09
Human Site: Y272 Identified Species: 28
UniProt: Q9H0C2 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H0C2 NP_112581.1 315 35022 Y272 L D C F V K I Y Q H E G I S S
Chimpanzee Pan troglodytes XP_001156886 315 34984 Y272 L D C F V K I Y Q H E G I S S
Rhesus Macaque Macaca mulatta XP_001105150 315 35056 Y272 L D C F V K I Y Q H E G I N S
Dog Lupus familis XP_540952 459 49686 Y412 L D C F V K I Y Q H E G V N A
Cat Felis silvestris
Mouse Mus musculus Q3V132 320 35239 Y273 I D C F L K I Y R H E G V P A
Rat Rattus norvegicus Q05962 298 32971 K260 G T V D C W R K I A K D E G R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001006443 298 32950 K260 G T I D C W K K I A K D E G S
Frog Xenopus laevis Q7T0U6 473 52371 L429 P Q L N M G G L F R K I V A K
Zebra Danio Brachydanio rerio Q66L49 477 53337 L431 E Q V S M S K L V K K I M Q K
Tiger Blowfish Takifugu rubipres NP_001037839 298 32885 K260 G T M D C W R K I A R D E G T
Fruit Fly Dros. melanogaster Q26365 312 34196 T274 N T L H C W A T I A K Q E G T
Honey Bee Apis mellifera NP_001010975 300 32968 T262 S T L H C W A T I Y K T E G G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P04709 387 42373 L341 L D A F Q Q I L K K E G P K S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P40941 385 41727 V339 F D A F S Q I V K K E G A K S
Baker's Yeast Sacchar. cerevisiae P18238 307 33294 V265 I D C L K K I V A S E G V G S
Red Bread Mold Neurospora crassa P02723 313 33870 V267 F D A A S Q I V A K E G V K S
Conservation
Percent
Protein Identity: 100 99.6 99.3 63.6 N.A. 87.5 68.2 N.A. N.A. 68.5 23 22.2 67.6 69.2 70.1 N.A. N.A.
Protein Similarity: 100 99.6 99.6 67 N.A. 93.7 79.6 N.A. N.A. 80.3 37 36.2 80.3 80.6 81.5 N.A. N.A.
P-Site Identity: 100 100 93.3 80 N.A. 60 0 N.A. N.A. 6.6 0 0 0 0 0 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 6.6 N.A. N.A. 13.3 26.6 20 6.6 13.3 13.3 N.A. N.A.
Percent
Protein Identity: N.A. 44.4 N.A. 45.7 52 53.3
Protein Similarity: N.A. 56.8 N.A. 55 65.4 65.4
P-Site Identity: N.A. 46.6 N.A. 40 46.6 33.3
P-Site Similarity: N.A. 60 N.A. 53.3 60 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 19 7 0 0 13 0 13 25 0 0 7 7 13 % A
% Cys: 0 0 38 0 32 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 57 0 19 0 0 0 0 0 0 0 19 0 0 0 % D
% Glu: 7 0 0 0 0 0 0 0 0 0 57 0 32 0 0 % E
% Phe: 13 0 0 44 0 0 0 0 7 0 0 0 0 0 0 % F
% Gly: 19 0 0 0 0 7 7 0 0 0 0 57 0 38 7 % G
% His: 0 0 0 13 0 0 0 0 0 32 0 0 0 0 0 % H
% Ile: 13 0 7 0 0 0 57 0 32 0 0 13 19 0 0 % I
% Lys: 0 0 0 0 7 38 13 19 13 25 38 0 0 19 13 % K
% Leu: 32 0 19 7 7 0 0 19 0 0 0 0 0 0 0 % L
% Met: 0 0 7 0 13 0 0 0 0 0 0 0 7 0 0 % M
% Asn: 7 0 0 7 0 0 0 0 0 0 0 0 0 13 0 % N
% Pro: 7 0 0 0 0 0 0 0 0 0 0 0 7 7 0 % P
% Gln: 0 13 0 0 7 19 0 0 25 0 0 7 0 7 0 % Q
% Arg: 0 0 0 0 0 0 13 0 7 7 7 0 0 0 7 % R
% Ser: 7 0 0 7 13 7 0 0 0 7 0 0 0 13 50 % S
% Thr: 0 32 0 0 0 0 0 13 0 0 0 7 0 0 13 % T
% Val: 0 0 13 0 25 0 0 19 7 0 0 0 32 0 0 % V
% Trp: 0 0 0 0 0 32 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 32 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _