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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM117
All Species:
9.09
Human Site:
Y431
Identified Species:
33.33
UniProt:
Q9H0C3
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H0C3
NP_115632.1
514
60185
Y431
M
E
N
Q
D
K
T
Y
T
R
M
K
R
K
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001092306
514
60138
Y431
M
E
N
Q
D
K
T
Y
T
R
M
K
R
K
S
Dog
Lupus familis
XP_852094
347
40667
F265
I
A
F
V
W
F
G
F
F
I
W
F
F
G
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH18
514
60338
Y431
M
E
N
Q
D
K
T
Y
T
R
M
K
R
K
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416041
558
64868
K475
Q
G
M
E
N
L
D
K
S
Y
T
R
M
K
R
Frog
Xenopus laevis
NP_001090438
504
58917
F416
F
I
S
F
F
G
R
F
K
K
S
E
Q
G
M
Zebra Danio
Brachydanio rerio
Q7ZVW1
401
47554
I319
K
E
E
Y
H
I
H
I
T
G
K
W
F
N
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.8
65.9
N.A.
95.9
N.A.
N.A.
N.A.
78.3
74.9
57.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
100
66.3
N.A.
97
N.A.
N.A.
N.A.
83.5
85.5
66.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
100
0
N.A.
100
N.A.
N.A.
N.A.
6.6
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
13.3
N.A.
100
N.A.
N.A.
N.A.
33.3
33.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
43
0
15
0
0
0
0
0
0
0
0
% D
% Glu:
0
58
15
15
0
0
0
0
0
0
0
15
0
0
0
% E
% Phe:
15
0
15
15
15
15
0
29
15
0
0
15
29
0
0
% F
% Gly:
0
15
0
0
0
15
15
0
0
15
0
0
0
29
0
% G
% His:
0
0
0
0
15
0
15
0
0
0
0
0
0
0
0
% H
% Ile:
15
15
0
0
0
15
0
15
0
15
0
0
0
0
0
% I
% Lys:
15
0
0
0
0
43
0
15
15
15
15
43
0
58
0
% K
% Leu:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% L
% Met:
43
0
15
0
0
0
0
0
0
0
43
0
15
0
15
% M
% Asn:
0
0
43
0
15
0
0
0
0
0
0
0
0
15
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
15
0
0
43
0
0
0
0
0
0
0
0
15
0
0
% Q
% Arg:
0
0
0
0
0
0
15
0
0
43
0
15
43
0
29
% R
% Ser:
0
0
15
0
0
0
0
0
15
0
15
0
0
0
43
% S
% Thr:
0
0
0
0
0
0
43
0
58
0
15
0
0
0
0
% T
% Val:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
15
0
0
0
0
0
15
15
0
0
0
% W
% Tyr:
0
0
0
15
0
0
0
43
0
15
0
0
0
0
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _