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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ILKAP All Species: 31.52
Human Site: S305 Identified Species: 49.52
UniProt: Q9H0C8 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.21
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H0C8 NP_110395.1 392 42907 S305 Y K R C G V T S V P D I R R C
Chimpanzee Pan troglodytes XP_001152781 553 60157 S466 Y K R C G V T S V P D I R R C
Rhesus Macaque Macaca mulatta XP_001094705 590 64766 S503 Y K R C G V T S V P D I R R C
Dog Lupus familis XP_543305 401 43921 S305 Y K R C G V T S V P D I R R C
Cat Felis silvestris
Mouse Mus musculus Q8R0F6 392 42756 S305 Y K R C G V T S V P D I R R C
Rat Rattus norvegicus Q9Z1Z6 392 42726 S305 Y K R C G V T S V P D I R R C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513557 590 63726 S348 Y K R C G V T S V P D I K R C
Chicken Gallus gallus XP_422661 389 42657 S302 Y K R C G V I S V P D I K R C
Frog Xenopus laevis NP_001086890 344 37998 K262 V I S T P E V K R C P L T D S
Zebra Danio Brachydanio rerio NP_001082973 129 14081 H47 F A A E N L H H T L L S K F P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_496370 242 26827 D160 I Y V A N I G D S R A V V A R
Sea Urchin Strong. purpuratus XP_001180671 354 39861 C272 F K R S G V I C T P D I K K C
Poplar Tree Populus trichocarpa XP_002321498 266 28901 K184 F G D R Q F K K V G V V A T P
Maize Zea mays NP_001130289 360 39005 R275 V S R A F G D R Q F K K V G L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LMT1 351 38467 K268 A F G D R H F K K F G V S A T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70.3 65 94.2 N.A. 95.1 95.1 N.A. 60.1 84.1 58.1 23.7 N.A. N.A. N.A. 28.8 47.7
Protein Similarity: 100 70.5 65.2 95.2 N.A. 97.6 96.9 N.A. 62.8 88.5 72.6 29.3 N.A. N.A. N.A. 42.5 65
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 93.3 86.6 0 0 N.A. N.A. N.A. 0 53.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 93.3 6.6 20 N.A. N.A. N.A. 13.3 73.3
Percent
Protein Identity: 26.7 33.1 N.A. 32.4 N.A. N.A.
Protein Similarity: 38.2 53.8 N.A. 52.8 N.A. N.A.
P-Site Identity: 6.6 6.6 N.A. 0 N.A. N.A.
P-Site Similarity: 20 6.6 N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 7 14 0 0 0 0 0 0 7 0 7 14 0 % A
% Cys: 0 0 0 54 0 0 0 7 0 7 0 0 0 0 60 % C
% Asp: 0 0 7 7 0 0 7 7 0 0 60 0 0 7 0 % D
% Glu: 0 0 0 7 0 7 0 0 0 0 0 0 0 0 0 % E
% Phe: 20 7 0 0 7 7 7 0 0 14 0 0 0 7 0 % F
% Gly: 0 7 7 0 60 7 7 0 0 7 7 0 0 7 0 % G
% His: 0 0 0 0 0 7 7 7 0 0 0 0 0 0 0 % H
% Ile: 7 7 0 0 0 7 14 0 0 0 0 60 0 0 0 % I
% Lys: 0 60 0 0 0 0 7 20 7 0 7 7 27 7 0 % K
% Leu: 0 0 0 0 0 7 0 0 0 7 7 7 0 0 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 14 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 7 0 0 0 0 60 7 0 0 0 14 % P
% Gln: 0 0 0 0 7 0 0 0 7 0 0 0 0 0 0 % Q
% Arg: 0 0 67 7 7 0 0 7 7 7 0 0 40 54 7 % R
% Ser: 0 7 7 7 0 0 0 54 7 0 0 7 7 0 7 % S
% Thr: 0 0 0 7 0 0 47 0 14 0 0 0 7 7 7 % T
% Val: 14 0 7 0 0 60 7 0 60 0 7 20 14 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 54 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _