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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ILKAP All Species: 19.09
Human Site: S89 Identified Species: 30
UniProt: Q9H0C8 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H0C8 NP_110395.1 392 42907 S89 S E E E K N G S E E L V E K K
Chimpanzee Pan troglodytes XP_001152781 553 60157 S252 S E E E K N G S E E L V E K K
Rhesus Macaque Macaca mulatta XP_001094705 590 64766 S289 S E E E K N G S E E L V E K K
Dog Lupus familis XP_543305 401 43921 S89 S E E E K N G S E E L V E K K
Cat Felis silvestris
Mouse Mus musculus Q8R0F6 392 42756 G89 P E E E K N G G E E L V E K K
Rat Rattus norvegicus Q9Z1Z6 392 42726 G89 P E E E K N G G E E L V E K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513557 590 63726 S132 S E E E K N G S E E R V E K K
Chicken Gallus gallus XP_422661 389 42657 R86 E E E E K N G R E E L V E K K
Frog Xenopus laevis NP_001086890 344 37998 E70 H I A E R R G E R E E L Q D A
Zebra Danio Brachydanio rerio NP_001082973 129 14081
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_496370 242 26827
Sea Urchin Strong. purpuratus XP_001180671 354 39861 Y77 G M Y S L H G Y Y A E R K G E
Poplar Tree Populus trichocarpa XP_002321498 266 28901
Maize Zea mays NP_001130289 360 39005 V79 V L G E Q K M V L T V V E A D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LMT1 351 38467 D76 K E F L V E A D V A E D K G A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70.3 65 94.2 N.A. 95.1 95.1 N.A. 60.1 84.1 58.1 23.7 N.A. N.A. N.A. 28.8 47.7
Protein Similarity: 100 70.5 65.2 95.2 N.A. 97.6 96.9 N.A. 62.8 88.5 72.6 29.3 N.A. N.A. N.A. 42.5 65
P-Site Identity: 100 100 100 100 N.A. 86.6 86.6 N.A. 93.3 86.6 20 0 N.A. N.A. N.A. 0 6.6
P-Site Similarity: 100 100 100 100 N.A. 86.6 86.6 N.A. 93.3 86.6 40 0 N.A. N.A. N.A. 0 26.6
Percent
Protein Identity: 26.7 33.1 N.A. 32.4 N.A. N.A.
Protein Similarity: 38.2 53.8 N.A. 52.8 N.A. N.A.
P-Site Identity: 0 20 N.A. 6.6 N.A. N.A.
P-Site Similarity: 0 33.3 N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 0 0 7 0 0 14 0 0 0 7 14 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 7 0 0 0 7 0 7 7 % D
% Glu: 7 60 54 67 0 7 0 7 54 60 20 0 60 0 7 % E
% Phe: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 7 0 7 0 0 0 67 14 0 0 0 0 0 14 0 % G
% His: 7 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 7 0 0 0 54 7 0 0 0 0 0 0 14 54 54 % K
% Leu: 0 7 0 7 7 0 0 0 7 0 47 7 0 0 0 % L
% Met: 0 7 0 0 0 0 7 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 54 0 0 0 0 0 0 0 0 0 % N
% Pro: 14 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 7 0 0 0 0 0 0 0 7 0 0 % Q
% Arg: 0 0 0 0 7 7 0 7 7 0 7 7 0 0 0 % R
% Ser: 34 0 0 7 0 0 0 34 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % T
% Val: 7 0 0 0 7 0 0 7 7 0 7 60 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 0 0 0 7 7 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _