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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHARPIN
All Species:
0
Human Site:
S178
Identified Species:
0
UniProt:
Q9H0F6
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H0F6
NP_112236.3
387
39949
S178
E
R
E
E
L
A
G
S
L
A
R
A
I
A
G
Chimpanzee
Pan troglodytes
XP_001156216
357
36712
A176
L
T
E
R
E
E
L
A
G
S
L
A
R
A
I
Rhesus Macaque
Macaca mulatta
XP_001102921
382
39677
N173
E
R
E
E
L
A
G
N
L
A
R
A
I
A
G
Dog
Lupus familis
XP_532352
691
73197
R460
E
K
E
E
L
V
G
R
L
A
R
A
I
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q91WA6
380
39834
L176
K
E
E
L
A
T
R
L
S
Q
A
I
A
G
G
Rat
Rattus norvegicus
Q9EQL9
381
40268
H175
K
K
E
E
L
A
T
H
L
A
Q
A
I
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001104670
714
78894
A181
P
R
T
E
E
I
C
A
E
L
V
S
A
I
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.4
93.8
43.8
N.A.
73.3
72.8
N.A.
N.A.
N.A.
N.A.
23.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
90.6
95
47.9
N.A.
82.1
80.3
N.A.
N.A.
N.A.
N.A.
32.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
20
93.3
66.6
N.A.
13.3
66.6
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
100
73.3
N.A.
20
86.6
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
15
43
0
29
0
58
15
72
29
58
0
% A
% Cys:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% D
% Glu:
43
15
86
72
29
15
0
0
15
0
0
0
0
15
15
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
43
0
15
0
0
0
0
15
58
% G
% His:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
15
0
0
0
0
0
15
58
15
15
% I
% Lys:
29
29
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
15
0
0
15
58
0
15
15
58
15
15
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% N
% Pro:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
15
15
0
0
0
0
% Q
% Arg:
0
43
0
15
0
0
15
15
0
0
43
0
15
0
0
% R
% Ser:
0
0
0
0
0
0
0
15
15
15
0
15
0
0
0
% S
% Thr:
0
15
15
0
0
15
15
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
15
0
0
0
0
15
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _