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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL25
All Species:
37.58
Human Site:
S530
Identified Species:
82.67
UniProt:
Q9H0H3
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H0H3
NP_071925.2
589
65923
S530
D
M
T
A
K
R
M
S
C
H
A
L
A
S
G
Chimpanzee
Pan troglodytes
XP_510571
589
65852
S530
D
M
T
A
K
R
M
S
C
H
A
L
A
S
G
Rhesus Macaque
Macaca mulatta
XP_001086777
589
65843
S530
D
M
T
A
K
R
M
S
C
H
A
L
A
S
G
Dog
Lupus familis
XP_545843
589
65955
S530
D
M
T
A
K
R
M
S
C
H
A
L
A
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8R2P1
589
65808
S530
D
M
T
A
K
R
M
S
C
H
A
V
A
S
G
Rat
Rattus norvegicus
Q4KLM4
589
65822
S530
D
M
T
A
K
R
M
S
C
H
A
V
A
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506836
626
69387
S567
D
M
T
A
K
R
M
S
C
H
A
L
A
S
G
Chicken
Gallus gallus
XP_001233011
589
66175
S530
D
M
T
A
K
R
M
S
C
H
A
L
A
S
G
Frog
Xenopus laevis
Q6DFF7
589
66062
S530
D
M
T
A
K
R
M
S
C
H
A
L
A
S
G
Zebra Danio
Brachydanio rerio
Q5U374
564
62914
Y495
V
Y
N
I
R
T
D
Y
W
T
T
V
A
N
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
G550
A
M
T
S
R
R
S
G
V
G
L
A
V
V
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.4
97.7
N.A.
94.9
94.7
N.A.
80.9
90.1
84.8
29.5
N.A.
31.1
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
99.8
98.8
N.A.
97.2
97.6
N.A.
87.6
96.4
93
46.5
N.A.
48.3
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
100
100
100
6.6
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
26.6
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
82
0
0
0
0
0
0
82
10
91
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
82
0
0
0
0
0
0
% C
% Asp:
82
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
82
% G
% His:
0
0
0
0
0
0
0
0
0
82
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
82
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
10
64
0
0
0
% L
% Met:
0
91
0
0
0
0
82
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
19
91
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
10
0
0
10
82
0
0
0
0
0
82
0
% S
% Thr:
0
0
91
0
0
10
0
0
0
10
10
0
0
0
0
% T
% Val:
10
0
0
0
0
0
0
0
10
0
0
28
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _