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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PARP12
All Species:
21.21
Human Site:
T225
Identified Species:
51.85
UniProt:
Q9H0J9
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H0J9
NP_073587.1
701
79064
T225
D
L
V
S
R
L
P
T
I
Y
R
N
A
H
D
Chimpanzee
Pan troglodytes
XP_519422
703
79133
T225
D
L
V
S
R
L
P
T
I
Y
R
N
A
H
D
Rhesus Macaque
Macaca mulatta
XP_001108942
701
78961
S225
D
L
V
S
R
L
P
S
I
Y
R
N
A
H
D
Dog
Lupus familis
XP_539886
703
79106
S226
D
L
V
S
R
L
P
S
I
Y
R
N
A
H
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BZ20
711
79883
S234
D
L
V
S
R
L
L
S
T
Y
R
N
A
Y
D
Rat
Rattus norvegicus
Q8K3Y6
776
86752
C219
V
Q
N
I
Q
D
I
C
N
N
K
H
A
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517609
469
53681
K23
T
F
K
K
T
C
G
K
L
H
V
C
Q
F
Y
Chicken
Gallus gallus
XP_416333
751
86070
S302
D
I
I
Q
K
L
P
S
I
Y
R
N
M
Y
A
Frog
Xenopus laevis
NP_001088385
503
58277
V57
V
Q
E
G
D
Q
K
V
A
V
Y
R
S
D
L
Zebra Danio
Brachydanio rerio
XP_695578
663
75552
N214
A
R
G
L
S
A
E
N
M
R
R
L
L
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.1
96.7
83.9
N.A.
80.3
21.7
N.A.
39.2
51
36.9
44
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
95.3
97.8
90.9
N.A.
88.3
40
N.A.
49.6
62.9
49.3
62.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
93.3
N.A.
73.3
6.6
N.A.
0
46.6
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
86.6
26.6
N.A.
13.3
80
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
10
0
0
10
0
0
0
60
0
10
% A
% Cys:
0
0
0
0
0
10
0
10
0
0
0
10
0
0
0
% C
% Asp:
60
0
0
0
10
10
0
0
0
0
0
0
0
10
50
% D
% Glu:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
10
10
0
0
10
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
10
0
40
0
% H
% Ile:
0
10
10
10
0
0
10
0
50
0
0
0
0
0
0
% I
% Lys:
0
0
10
10
10
0
10
10
0
0
10
0
0
10
0
% K
% Leu:
0
50
0
10
0
60
10
0
10
0
0
10
10
0
20
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% M
% Asn:
0
0
10
0
0
0
0
10
10
10
0
60
0
0
0
% N
% Pro:
0
0
0
0
0
0
50
0
0
0
0
0
0
0
0
% P
% Gln:
0
20
0
10
10
10
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
10
0
0
50
0
0
0
0
10
70
10
0
10
10
% R
% Ser:
0
0
0
50
10
0
0
40
0
0
0
0
10
0
0
% S
% Thr:
10
0
0
0
10
0
0
20
10
0
0
0
0
0
0
% T
% Val:
20
0
50
0
0
0
0
10
0
10
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
60
10
0
0
20
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _