KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RSHL1
All Species:
10.91
Human Site:
S178
Identified Species:
30
UniProt:
Q9H0K4
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H0K4
NP_110412.1
717
80913
S178
P
A
L
Q
F
L
P
S
E
L
G
F
P
H
Y
Chimpanzee
Pan troglodytes
XP_524308
717
80907
S178
P
A
L
Q
F
L
P
S
E
L
G
F
P
H
Y
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533639
723
81933
S183
P
T
L
Q
Y
T
P
S
E
L
G
F
M
P
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDR2
708
80183
S171
P
S
L
H
L
R
P
S
D
L
G
F
M
P
I
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518144
452
51703
Chicken
Gallus gallus
XP_420671
648
72693
V157
L
Y
D
H
L
V
N
V
L
T
K
I
L
D
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923773
537
59934
E48
L
L
T
R
V
M
D
E
R
P
E
N
A
V
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624190
561
64759
E72
E
F
S
R
K
V
K
E
Q
R
F
K
T
K
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999761
552
62705
Y63
N
K
S
N
L
N
L
Y
D
H
L
S
R
I
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
N.A.
78.8
N.A.
75.3
N.A.
N.A.
42.9
52.8
N.A.
38.7
N.A.
N.A.
32.3
N.A.
44.7
Protein Similarity:
100
99.4
N.A.
86.5
N.A.
82.2
N.A.
N.A.
51
66.6
N.A.
50.9
N.A.
N.A.
48.4
N.A.
59.9
P-Site Identity:
100
100
N.A.
60
N.A.
46.6
N.A.
N.A.
0
0
N.A.
0
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
100
N.A.
73.3
N.A.
60
N.A.
N.A.
0
6.6
N.A.
13.3
N.A.
N.A.
20
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
23
0
0
0
0
0
0
0
0
0
0
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
12
0
0
0
12
0
23
0
0
0
0
12
12
% D
% Glu:
12
0
0
0
0
0
0
23
34
0
12
0
0
0
12
% E
% Phe:
0
12
0
0
23
0
0
0
0
0
12
45
0
0
12
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
45
0
0
0
0
% G
% His:
0
0
0
23
0
0
0
0
0
12
0
0
0
23
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
12
0
12
12
% I
% Lys:
0
12
0
0
12
0
12
0
0
0
12
12
0
12
0
% K
% Leu:
23
12
45
0
34
23
12
0
12
45
12
0
12
0
12
% L
% Met:
0
0
0
0
0
12
0
0
0
0
0
0
23
0
0
% M
% Asn:
12
0
0
12
0
12
12
0
0
0
0
12
0
0
0
% N
% Pro:
45
0
0
0
0
0
45
0
0
12
0
0
23
23
0
% P
% Gln:
0
0
0
34
0
0
0
0
12
0
0
0
0
0
0
% Q
% Arg:
0
0
0
23
0
12
0
0
12
12
0
0
12
0
0
% R
% Ser:
0
12
23
0
0
0
0
45
0
0
0
12
0
0
12
% S
% Thr:
0
12
12
0
0
12
0
0
0
12
0
0
12
0
0
% T
% Val:
0
0
0
0
12
23
0
12
0
0
0
0
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
0
0
12
0
0
12
0
0
0
0
0
0
23
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _