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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM49A
All Species:
22.12
Human Site:
S245
Identified Species:
54.07
UniProt:
Q9H0Q0
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H0Q0
NP_110424.1
323
37313
S245
E
Y
R
S
R
F
T
S
E
E
T
L
M
F
C
Chimpanzee
Pan troglodytes
XP_001154277
324
36802
N246
E
Y
R
S
R
F
T
N
E
E
T
V
S
F
C
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532880
363
41798
S285
E
Y
R
S
R
F
T
S
E
E
T
L
M
F
C
Cat
Felis silvestris
Mouse
Mus musculus
Q8BHZ0
323
37324
S245
E
Y
R
S
R
F
T
S
E
E
T
L
M
F
C
Rat
Rattus norvegicus
NP_001100188
323
37310
S245
E
Y
R
S
R
F
T
S
E
E
T
L
M
F
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516808
305
35126
N227
E
Y
R
S
R
F
T
N
E
D
T
L
M
F
C
Chicken
Gallus gallus
Q5ZI04
323
37295
S245
E
Y
R
S
R
F
T
S
E
E
T
L
M
F
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956402
323
37117
S245
E
Y
T
S
R
F
N
S
E
D
T
L
L
F
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623054
329
37276
R250
N
L
L
A
Q
F
Q
R
E
E
T
Q
L
F
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001175651
326
37287
E246
D
F
V
A
R
F
Q
E
R
N
T
V
L
F
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.3
N.A.
88.9
N.A.
99.6
99.6
N.A.
90.7
96.5
N.A.
86.3
N.A.
N.A.
54.4
N.A.
56.7
Protein Similarity:
100
90.4
N.A.
88.9
N.A.
99.6
100
N.A.
92.8
98.4
N.A.
94.4
N.A.
N.A.
70.8
N.A.
76.6
P-Site Identity:
100
80
N.A.
100
N.A.
100
100
N.A.
86.6
100
N.A.
73.3
N.A.
N.A.
33.3
N.A.
33.3
P-Site Similarity:
100
93.3
N.A.
100
N.A.
100
100
N.A.
100
100
N.A.
86.6
N.A.
N.A.
53.3
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
20
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
90
% C
% Asp:
10
0
0
0
0
0
0
0
0
20
0
0
0
0
0
% D
% Glu:
80
0
0
0
0
0
0
10
90
70
0
0
0
0
0
% E
% Phe:
0
10
0
0
0
100
0
0
0
0
0
0
0
100
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
10
0
0
0
0
0
0
0
0
70
30
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
60
0
0
% M
% Asn:
10
0
0
0
0
0
10
20
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
0
20
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
70
0
90
0
0
10
10
0
0
0
0
0
0
% R
% Ser:
0
0
0
80
0
0
0
60
0
0
0
0
10
0
0
% S
% Thr:
0
0
10
0
0
0
70
0
0
0
100
0
0
0
0
% T
% Val:
0
0
10
0
0
0
0
0
0
0
0
20
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
80
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _