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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM49A All Species: 40
Human Site: Y158 Identified Species: 97.78
UniProt: Q9H0Q0 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H0Q0 NP_110424.1 323 37313 Y158 I Q N D F S Y Y R R T I S R N
Chimpanzee Pan troglodytes XP_001154277 324 36802 Y159 I Q N D F S Y Y R R T L S R M
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532880 363 41798 Y198 I Q N D F S Y Y R R T I S R N
Cat Felis silvestris
Mouse Mus musculus Q8BHZ0 323 37324 Y158 I Q N D F S Y Y R R T I S R N
Rat Rattus norvegicus NP_001100188 323 37310 Y158 I Q N D F S Y Y R R T I S R N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516808 305 35126 Y140 I Q N D F S Y Y R R T I S R N
Chicken Gallus gallus Q5ZI04 323 37295 Y158 I Q N D F S Y Y R R T I S R N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_956402 323 37117 Y158 I Q N D F S Y Y R R T I S R N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623054 329 37276 Y162 I Q N D F S Y Y R R T L T R A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001175651 326 37287 Y159 I Q N D F S Y Y R R T L S R I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.3 N.A. 88.9 N.A. 99.6 99.6 N.A. 90.7 96.5 N.A. 86.3 N.A. N.A. 54.4 N.A. 56.7
Protein Similarity: 100 90.4 N.A. 88.9 N.A. 99.6 100 N.A. 92.8 98.4 N.A. 94.4 N.A. N.A. 70.8 N.A. 76.6
P-Site Identity: 100 86.6 N.A. 100 N.A. 100 100 N.A. 100 100 N.A. 100 N.A. N.A. 80 N.A. 86.6
P-Site Similarity: 100 93.3 N.A. 100 N.A. 100 100 N.A. 100 100 N.A. 100 N.A. N.A. 93.3 N.A. 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 100 0 0 0 0 0 0 0 0 0 0 70 0 0 10 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 30 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 100 0 0 0 0 0 0 0 0 0 0 0 70 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 100 100 0 0 0 100 0 % R
% Ser: 0 0 0 0 0 100 0 0 0 0 0 0 90 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 100 0 10 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 100 100 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _