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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MUDENG All Species: 24.24
Human Site: S219 Identified Species: 44.44
UniProt: Q9H0R1 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H0R1 NP_060699.3 490 54767 S219 S I T E K V K S M Q Y D K Q G
Chimpanzee Pan troglodytes XP_001163834 490 54762 S219 S I T E K V K S M Q Y D K Q G
Rhesus Macaque Macaca mulatta XP_001089352 492 55070 S221 S I T E K V K S M Q Y D K Q G
Dog Lupus familis XP_547833 491 54683 S219 S I T E K V K S M Q Y D K Q D
Cat Felis silvestris
Mouse Mus musculus Q8BJ63 490 54318 C219 S I T E T V K C M Q Y G K Q D
Rat Rattus norvegicus Q499N2 490 54421 S219 S I T E N V K S M Q Y G K Q D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516642 490 53794 S219 G I T E K V K S M Q Y D K R D
Chicken Gallus gallus XP_421441 484 54032 C214 C I T E K V K C M Q Y D K R D
Frog Xenopus laevis NP_001088546 487 54131 S216 S I T E N V E S T Q Y D K G D
Zebra Danio Brachydanio rerio NP_001018490 475 51305 A204 Q K Q P A W K A G V H R G R A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001187307 523 57266 A225 A T T E Q I R A V L Y N R S D
Poplar Tree Populus trichocarpa XP_002314429 433 46528 Q163 L P P A D L K Q P A W K P Y L
Maize Zea mays NP_001147471 629 68495 I323 L F S S L E T I N A A L Y D R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 93.2 91.4 N.A. 85 84.9 N.A. 72.6 62.4 61.4 54.6 N.A. N.A. N.A. N.A. 28.4
Protein Similarity: 100 100 94.7 96.1 N.A. 90.6 91.6 N.A. 83.4 78.9 76.9 69.5 N.A. N.A. N.A. N.A. 49.3
P-Site Identity: 100 100 100 93.3 N.A. 73.3 80 N.A. 80 73.3 66.6 6.6 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 100 100 93.3 N.A. 73.3 80 N.A. 86.6 80 73.3 26.6 N.A. N.A. N.A. N.A. 73.3
Percent
Protein Identity: 21.6 20.8 N.A. N.A. N.A. N.A.
Protein Similarity: 38.1 35.7 N.A. N.A. N.A. N.A.
P-Site Identity: 6.6 0 N.A. N.A. N.A. N.A.
P-Site Similarity: 20 6.6 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 8 8 0 0 16 0 16 8 0 0 0 8 % A
% Cys: 8 0 0 0 0 0 0 16 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 0 0 0 0 0 0 54 0 8 54 % D
% Glu: 0 0 0 77 0 8 8 0 0 0 0 0 0 0 0 % E
% Phe: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 0 0 0 0 0 0 8 0 0 16 8 8 24 % G
% His: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 0 70 0 0 0 8 0 8 0 0 0 0 0 0 0 % I
% Lys: 0 8 0 0 47 0 77 0 0 0 0 8 70 0 0 % K
% Leu: 16 0 0 0 8 8 0 0 0 8 0 8 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 62 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 16 0 0 0 8 0 0 8 0 0 0 % N
% Pro: 0 8 8 8 0 0 0 0 8 0 0 0 8 0 0 % P
% Gln: 8 0 8 0 8 0 0 8 0 70 0 0 0 47 0 % Q
% Arg: 0 0 0 0 0 0 8 0 0 0 0 8 8 24 8 % R
% Ser: 54 0 8 8 0 0 0 54 0 0 0 0 0 8 0 % S
% Thr: 0 8 77 0 8 0 8 0 8 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 70 0 0 8 8 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 8 0 0 0 0 8 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 77 0 8 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _