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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MUDENG
All Species:
33.03
Human Site:
S374
Identified Species:
60.56
UniProt:
Q9H0R1
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H0R1
NP_060699.3
490
54767
S374
T
H
L
E
Y
K
T
S
F
G
Q
L
E
V
F
Chimpanzee
Pan troglodytes
XP_001163834
490
54762
S374
T
H
L
E
Y
K
T
S
F
G
Q
L
E
V
F
Rhesus Macaque
Macaca mulatta
XP_001089352
492
55070
S376
T
H
L
E
Y
K
T
S
F
G
Q
L
E
V
F
Dog
Lupus familis
XP_547833
491
54683
S374
T
H
V
E
S
K
V
S
F
G
Q
L
E
V
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8BJ63
490
54318
S374
T
H
L
E
Y
K
A
S
F
G
Q
L
E
V
F
Rat
Rattus norvegicus
Q499N2
490
54421
S374
T
H
L
E
Y
K
V
S
F
G
Q
L
E
V
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516642
490
53794
S374
T
H
L
E
Y
K
V
S
S
G
Q
L
D
L
S
Chicken
Gallus gallus
XP_421441
484
54032
S369
A
H
L
E
C
K
V
S
Y
G
Q
L
D
L
S
Frog
Xenopus laevis
NP_001088546
487
54131
S371
K
H
L
E
Y
K
V
S
H
G
Q
L
E
L
S
Zebra Danio
Brachydanio rerio
NP_001018490
475
51305
K359
L
I
G
S
V
E
V
K
V
S
S
G
Q
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001187307
523
57266
T380
S
E
R
S
S
S
P
T
P
S
Q
L
S
F
Q
Poplar Tree
Populus trichocarpa
XP_002314429
433
46528
R318
V
T
M
P
F
P
R
R
R
V
V
S
F
D
G
Maize
Zea mays
NP_001147471
629
68495
E478
S
M
T
E
H
S
I
E
W
R
I
V
S
S
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
93.2
91.4
N.A.
85
84.9
N.A.
72.6
62.4
61.4
54.6
N.A.
N.A.
N.A.
N.A.
28.4
Protein Similarity:
100
100
94.7
96.1
N.A.
90.6
91.6
N.A.
83.4
78.9
76.9
69.5
N.A.
N.A.
N.A.
N.A.
49.3
P-Site Identity:
100
100
100
80
N.A.
93.3
93.3
N.A.
66.6
53.3
66.6
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
80
73.3
73.3
20
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
21.6
20.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
38.1
35.7
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
13.3
33.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
16
8
0
% D
% Glu:
0
8
0
77
0
8
0
8
0
0
0
0
54
0
8
% E
% Phe:
0
0
0
0
8
0
0
0
47
0
0
0
8
8
47
% F
% Gly:
0
0
8
0
0
0
0
0
0
70
0
8
0
0
16
% G
% His:
0
70
0
0
8
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
8
0
0
0
8
0
0
0
0
% I
% Lys:
8
0
0
0
0
70
0
8
0
0
0
0
0
0
0
% K
% Leu:
8
0
62
0
0
0
0
0
0
0
0
77
0
31
0
% L
% Met:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
8
0
8
8
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
77
0
8
0
8
% Q
% Arg:
0
0
8
0
0
0
8
8
8
8
0
0
0
0
0
% R
% Ser:
16
0
0
16
16
16
0
70
8
16
8
8
16
8
24
% S
% Thr:
54
8
8
0
0
0
24
8
0
0
0
0
0
0
0
% T
% Val:
8
0
8
0
8
0
47
0
8
8
8
8
0
47
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
54
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _