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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MUDENG All Species: 31.82
Human Site: Y326 Identified Species: 58.33
UniProt: Q9H0R1 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H0R1 NP_060699.3 490 54767 Y326 V P P I L G F Y Q M K E E E V
Chimpanzee Pan troglodytes XP_001163834 490 54762 Y326 V P P I L G F Y Q M K E E E V
Rhesus Macaque Macaca mulatta XP_001089352 492 55070 Y328 V P P I L G F Y Q L K E E E V
Dog Lupus familis XP_547833 491 54683 Y326 V P P I L G F Y Q M K E E E I
Cat Felis silvestris
Mouse Mus musculus Q8BJ63 490 54318 Y326 V P P I L G S Y H M K E E G V
Rat Rattus norvegicus Q499N2 490 54421 Y326 V P P I L G S Y H M K E D G A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516642 490 53794 Y326 V P P I L G F Y Q L K E E E G
Chicken Gallus gallus XP_421441 484 54032 Y321 V P P I L G C Y Q L I E E G S
Frog Xenopus laevis NP_001088546 487 54131 Y323 V P P I L G F Y Q M T E E G S
Zebra Danio Brachydanio rerio NP_001018490 475 51305 G311 V P V P P I L G S Y Q L K A E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001187307 523 57266 P332 V T S P S R P P S V T M A R S
Poplar Tree Populus trichocarpa XP_002314429 433 46528 F270 R Y Q A N C G F G P P I K G F
Maize Zea mays NP_001147471 629 68495 F430 E N E G A F L F K L S L M E G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 93.2 91.4 N.A. 85 84.9 N.A. 72.6 62.4 61.4 54.6 N.A. N.A. N.A. N.A. 28.4
Protein Similarity: 100 100 94.7 96.1 N.A. 90.6 91.6 N.A. 83.4 78.9 76.9 69.5 N.A. N.A. N.A. N.A. 49.3
P-Site Identity: 100 100 93.3 93.3 N.A. 80 66.6 N.A. 86.6 66.6 80 13.3 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 80 73.3 N.A. 93.3 73.3 80 26.6 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: 21.6 20.8 N.A. N.A. N.A. N.A.
Protein Similarity: 38.1 35.7 N.A. N.A. N.A. N.A.
P-Site Identity: 0 6.6 N.A. N.A. N.A. N.A.
P-Site Similarity: 13.3 26.6 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 8 0 0 0 0 0 0 0 8 8 8 % A
% Cys: 0 0 0 0 0 8 8 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % D
% Glu: 8 0 8 0 0 0 0 0 0 0 0 70 62 47 8 % E
% Phe: 0 0 0 0 0 8 47 16 0 0 0 0 0 0 8 % F
% Gly: 0 0 0 8 0 70 8 8 8 0 0 0 0 39 16 % G
% His: 0 0 0 0 0 0 0 0 16 0 0 0 0 0 0 % H
% Ile: 0 0 0 70 0 8 0 0 0 0 8 8 0 0 8 % I
% Lys: 0 0 0 0 0 0 0 0 8 0 54 0 16 0 0 % K
% Leu: 0 0 0 0 70 0 16 0 0 31 0 16 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 47 0 8 8 0 0 % M
% Asn: 0 8 0 0 8 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 77 70 16 8 0 8 8 0 8 8 0 0 0 0 % P
% Gln: 0 0 8 0 0 0 0 0 54 0 8 0 0 0 0 % Q
% Arg: 8 0 0 0 0 8 0 0 0 0 0 0 0 8 0 % R
% Ser: 0 0 8 0 8 0 16 0 16 0 8 0 0 0 24 % S
% Thr: 0 8 0 0 0 0 0 0 0 0 16 0 0 0 0 % T
% Val: 85 0 8 0 0 0 0 0 0 8 0 0 0 0 31 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 70 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _