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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HDHD2
All Species:
43.03
Human Site:
Y124
Identified Species:
86.06
UniProt:
Q9H0R4
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H0R4
NP_115500.1
259
28536
Y124
L
A
P
E
H
F
H
Y
Q
I
L
N
Q
A
F
Chimpanzee
Pan troglodytes
XP_001148863
259
28556
Y124
L
A
P
E
H
F
H
Y
Q
I
L
N
Q
A
F
Rhesus Macaque
Macaca mulatta
XP_001086150
262
28794
Y127
L
A
P
E
H
F
H
Y
Q
I
L
N
Q
A
F
Dog
Lupus familis
XP_537270
263
28924
Y124
L
A
P
E
H
F
H
Y
Q
I
L
N
Q
A
F
Cat
Felis silvestris
Mouse
Mus musculus
Q3UGR5
259
28712
Y124
L
A
P
E
H
F
H
Y
Q
L
L
N
Q
A
F
Rat
Rattus norvegicus
Q6AYR6
259
28761
Y124
L
A
P
E
H
F
H
Y
Q
L
L
N
E
A
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505830
259
28329
Y124
L
A
P
D
H
F
N
Y
Q
V
L
N
Q
A
F
Chicken
Gallus gallus
XP_414700
259
28308
Y124
L
A
P
E
H
F
H
Y
E
M
M
N
K
A
F
Frog
Xenopus laevis
Q3B8E3
270
29197
Y130
D
A
A
E
N
F
S
Y
K
N
V
N
R
A
F
Zebra Danio
Brachydanio rerio
Q5BJJ5
262
28527
Y124
L
A
P
D
H
F
N
Y
Q
T
L
N
K
A
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392391
257
28168
Y124
L
A
P
D
K
F
H
Y
E
E
L
T
K
A
F
Nematode Worm
Caenorhab. elegans
NP_504597
257
28216
D120
L
A
P
E
K
F
N
D
T
T
L
T
H
A
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
96.5
93.5
N.A.
89.1
89.9
N.A.
88
83
42.2
76.3
N.A.
N.A.
56.7
49.4
N.A.
Protein Similarity:
100
99.6
98.4
97.7
N.A.
95.7
96.1
N.A.
96.1
91.8
62.2
86.2
N.A.
N.A.
72.1
66.8
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
86.6
N.A.
80
73.3
46.6
73.3
N.A.
N.A.
60
53.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
73.3
93.3
N.A.
N.A.
80
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
100
9
0
0
0
0
0
0
0
0
0
0
100
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
25
0
0
0
9
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
75
0
0
0
0
17
9
0
0
9
0
0
% E
% Phe:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
100
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
75
0
67
0
0
0
0
0
9
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
34
0
0
0
0
0
% I
% Lys:
0
0
0
0
17
0
0
0
9
0
0
0
25
0
0
% K
% Leu:
92
0
0
0
0
0
0
0
0
17
84
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
25
0
0
9
0
84
0
0
0
% N
% Pro:
0
0
92
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
67
0
0
0
50
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% R
% Ser:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
9
17
0
17
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
92
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _