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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM168
All Species:
17.88
Human Site:
Y257
Identified Species:
39.33
UniProt:
Q9H0V1
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H0V1
NP_071929.3
697
79755
Y257
E
R
W
K
P
F
L
Y
R
G
R
I
C
R
R
Chimpanzee
Pan troglodytes
XP_001167860
681
77830
R248
Y
R
G
R
I
C
R
R
L
S
V
V
F
A
G
Rhesus Macaque
Macaca mulatta
XP_001100216
697
79736
Y257
E
R
W
K
P
F
L
Y
R
G
R
I
C
R
R
Dog
Lupus familis
XP_854787
354
40067
Cat
Felis silvestris
Mouse
Mus musculus
Q91VX9
697
79655
H257
E
R
W
K
P
F
L
H
R
G
R
I
C
R
R
Rat
Rattus norvegicus
Q5PQM0
697
79753
Y257
E
R
W
K
P
F
L
Y
R
G
R
I
C
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516875
697
78850
F257
E
R
W
Q
P
Y
L
F
R
G
R
L
C
R
R
Chicken
Gallus gallus
XP_416021
700
79305
Y260
E
R
W
K
P
Y
L
Y
R
G
K
I
C
R
R
Frog
Xenopus laevis
Q7ZY86
700
79904
Y260
E
R
W
K
P
Y
L
Y
R
G
R
F
C
R
R
Zebra Danio
Brachydanio rerio
Q1LUD1
681
76558
G246
W
K
Q
F
L
S
A
G
R
L
W
R
R
F
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789985
685
76401
A251
L
L
L
L
L
A
I
A
F
E
V
L
F
L
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
99.5
49.2
N.A.
95.4
95.9
N.A.
86.6
85.4
79.7
59.1
N.A.
N.A.
N.A.
N.A.
42.6
Protein Similarity:
100
97.6
100
49.9
N.A.
98.4
98.5
N.A.
93.4
92.7
91.1
76.3
N.A.
N.A.
N.A.
N.A.
60.2
P-Site Identity:
100
6.6
100
0
N.A.
93.3
100
N.A.
73.3
86.6
86.6
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
20
100
0
N.A.
100
100
N.A.
100
100
93.3
13.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
10
10
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
64
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
64
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% E
% Phe:
0
0
0
10
0
37
0
10
10
0
0
10
19
10
0
% F
% Gly:
0
0
10
0
0
0
0
10
0
64
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
10
0
0
0
0
46
0
0
10
% I
% Lys:
0
10
0
55
0
0
0
0
0
0
10
0
0
0
0
% K
% Leu:
10
10
10
10
19
0
64
0
10
10
0
19
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
64
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
73
0
10
0
0
10
10
73
0
55
10
10
64
64
% R
% Ser:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
19
10
0
0
0
% V
% Trp:
10
0
64
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
10
0
0
0
0
28
0
46
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _