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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMG9
All Species:
26.36
Human Site:
S468
Identified Species:
52.73
UniProt:
Q9H0W8
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H0W8
NP_061981.2
520
57651
S468
R
G
H
P
S
F
Q
S
L
V
S
K
L
R
S
Chimpanzee
Pan troglodytes
XP_001158051
495
54769
P443
S
E
A
E
S
E
N
P
P
R
A
G
P
G
S
Rhesus Macaque
Macaca mulatta
XP_001106959
520
57618
S468
R
G
H
P
S
F
Q
S
L
V
S
K
L
R
S
Dog
Lupus familis
XP_533650
520
57589
S468
R
G
H
P
S
F
Q
S
L
V
S
K
L
R
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9DB90
520
57602
S468
R
G
H
P
S
F
Q
S
L
V
S
K
L
R
S
Rat
Rattus norvegicus
Q5PQS6
520
57614
S468
R
G
H
P
S
F
Q
S
L
V
S
K
L
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515769
130
14079
Q79
A
M
D
P
V
V
G
Q
A
K
L
L
P
P
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Q05AW9
508
56581
S456
K
G
H
P
S
F
H
S
L
V
S
R
L
R
S
Zebra Danio
Brachydanio rerio
XP_001923815
503
56076
S451
R
G
H
P
N
F
S
S
L
V
S
K
F
R
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395241
359
40784
A308
M
S
N
H
S
M
E
A
G
L
N
L
F
F
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780386
532
57732
R480
V
G
H
P
R
P
E
R
L
V
A
A
F
R
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001143814
423
45897
I372
L
G
M
I
R
D
Q
I
L
S
W
P
A
R
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95
99.2
98.2
N.A.
97.3
96.9
N.A.
21.9
N.A.
74.8
72.6
N.A.
N.A.
29.4
N.A.
37.4
Protein Similarity:
100
95.1
99.6
98.6
N.A.
98.4
98.4
N.A.
22.5
N.A.
85.5
85.3
N.A.
N.A.
44.8
N.A.
53.2
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
6.6
N.A.
80
80
N.A.
N.A.
6.6
N.A.
40
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
6.6
N.A.
93.3
86.6
N.A.
N.A.
40
N.A.
60
Percent
Protein Identity:
N.A.
24.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
39.8
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
0
0
0
9
9
0
17
9
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
9
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
9
0
9
0
9
17
0
0
0
0
0
0
0
9
% E
% Phe:
0
0
0
0
0
59
0
0
0
0
0
0
25
9
0
% F
% Gly:
0
75
0
0
0
0
9
0
9
0
0
9
0
9
0
% G
% His:
0
0
67
9
0
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
0
0
9
0
0
0
0
0
0
9
% I
% Lys:
9
0
0
0
0
0
0
0
0
9
0
50
0
0
0
% K
% Leu:
9
0
0
0
0
0
0
0
75
9
9
17
50
0
0
% L
% Met:
9
9
9
0
0
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
9
0
9
0
0
0
9
0
0
0
9
% N
% Pro:
0
0
0
75
0
9
0
9
9
0
0
9
17
9
0
% P
% Gln:
0
0
0
0
0
0
50
9
0
0
0
0
0
0
0
% Q
% Arg:
50
0
0
0
17
0
0
9
0
9
0
9
0
75
0
% R
% Ser:
9
9
0
0
67
0
9
59
0
9
59
0
0
0
75
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
9
0
0
0
9
9
0
0
0
67
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _