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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CSTL1
All Species:
0.91
Human Site:
S105
Identified Species:
2.5
UniProt:
Q9H114
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H114
NP_612140.1
145
16989
S105
N
S
S
C
P
L
Q
S
K
K
L
R
K
S
L
Chimpanzee
Pan troglodytes
XP_001146859
111
12788
T76
R
S
Q
M
Q
L
T
T
G
V
E
Y
V
V
T
Rhesus Macaque
Macaca mulatta
O19092
146
15839
L106
C
T
K
T
Q
P
N
L
D
N
C
P
F
H
E
Dog
Lupus familis
XP_848382
255
29349
P219
S
T
T
K
N
S
C
P
I
Q
S
K
N
K
L
Cat
Felis silvestris
Mouse
Mus musculus
P21460
140
15512
L100
C
T
K
S
Q
T
N
L
T
D
C
P
F
H
D
Rat
Rattus norvegicus
P14841
140
15418
L100
C
T
K
S
Q
T
N
L
T
N
C
P
F
H
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P01038
139
15268
L101
C
P
K
S
S
G
D
L
Q
S
C
E
F
H
D
Frog
Xenopus laevis
NP_001091281
149
17282
Q111
N
L
D
Q
C
D
F
Q
Q
D
S
P
L
K
Q
Zebra Danio
Brachydanio rerio
NP_001026843
128
14125
E91
C
R
K
G
G
V
E
E
L
C
A
I
H
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.4
30.8
39.6
N.A.
27.5
28.9
N.A.
N.A.
30.3
21.4
25.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
75.8
50
48.2
N.A.
48.9
50.3
N.A.
N.A.
49.6
46.3
40
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
0
6.6
N.A.
0
0
N.A.
N.A.
0
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
6.6
40
N.A.
6.6
6.6
N.A.
N.A.
6.6
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% A
% Cys:
56
0
0
12
12
0
12
0
0
12
45
0
0
0
0
% C
% Asp:
0
0
12
0
0
12
12
0
12
23
0
0
0
0
34
% D
% Glu:
0
0
0
0
0
0
12
12
0
0
12
12
0
12
12
% E
% Phe:
0
0
0
0
0
0
12
0
0
0
0
0
45
0
0
% F
% Gly:
0
0
0
12
12
12
0
0
12
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
12
45
0
% H
% Ile:
0
0
0
0
0
0
0
0
12
0
0
12
0
0
0
% I
% Lys:
0
0
56
12
0
0
0
0
12
12
0
12
12
23
0
% K
% Leu:
0
12
0
0
0
23
0
45
12
0
12
0
12
0
23
% L
% Met:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
23
0
0
0
12
0
34
0
0
23
0
0
12
0
12
% N
% Pro:
0
12
0
0
12
12
0
12
0
0
0
45
0
0
0
% P
% Gln:
0
0
12
12
45
0
12
12
23
12
0
0
0
0
12
% Q
% Arg:
12
12
0
0
0
0
0
0
0
0
0
12
0
0
0
% R
% Ser:
12
23
12
34
12
12
0
12
0
12
23
0
0
12
0
% S
% Thr:
0
45
12
12
0
23
12
12
23
0
0
0
0
0
12
% T
% Val:
0
0
0
0
0
12
0
0
0
12
0
0
12
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _