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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ING2 All Species: 7.27
Human Site: S131 Identified Species: 14.55
UniProt: Q9H160 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H160 NP_001555.1 280 32808 S131 C F Q D P A E S E R A S D K A
Chimpanzee Pan troglodytes XP_001139734 262 29553 E120 G A D R P K G E A A A Q A D K
Rhesus Macaque Macaca mulatta XP_001084274 279 31903 A131 G N S G K A G A D R P K G E A
Dog Lupus familis XP_540031 280 32729 G131 C F Q D P A E G E R A S D K G
Cat Felis silvestris
Mouse Mus musculus Q9ESK4 281 32974 S132 C F Q D P A E S E R A S D K S
Rat Rattus norvegicus Q498T3 421 46906 T193 G C R N N N S T A S C N N A Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515013 363 40927 A213 P T G N G G K A G P E K A K N
Chicken Gallus gallus Q5ZKY4 249 28538 E113 R F E A D L K E K Q I E S S D
Frog Xenopus laevis Q7ZX31 416 46165 S193 G C R T N L S S S S T N N V Y
Zebra Danio Brachydanio rerio NP_001002448 278 32265 V120 C F L E P G D V E R P P E K V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394517 279 32379 Q120 L G I A F F L Q P K R A R R T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792118 254 29513 K118 T H L E I T E K P E H P P D P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 52.1 60.7 97.5 N.A. 96.8 22.5 N.A. 45.1 34.2 23.3 72.5 N.A. N.A. 42.1 N.A. 41.4
Protein Similarity: 100 67.8 77.5 97.8 N.A. 98.5 39.9 N.A. 58.1 52.5 40.6 83.2 N.A. N.A. 62.1 N.A. 59.2
P-Site Identity: 100 13.3 20 86.6 N.A. 93.3 0 N.A. 6.6 6.6 6.6 40 N.A. N.A. 0 N.A. 6.6
P-Site Similarity: 100 13.3 40 86.6 N.A. 100 33.3 N.A. 26.6 33.3 26.6 60 N.A. N.A. 20 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 17 0 34 0 17 17 9 34 9 17 9 17 % A
% Cys: 34 17 0 0 0 0 0 0 0 0 9 0 0 0 0 % C
% Asp: 0 0 9 25 9 0 9 0 9 0 0 0 25 17 9 % D
% Glu: 0 0 9 17 0 0 34 17 34 9 9 9 9 9 0 % E
% Phe: 0 42 0 0 9 9 0 0 0 0 0 0 0 0 0 % F
% Gly: 34 9 9 9 9 17 17 9 9 0 0 0 9 0 9 % G
% His: 0 9 0 0 0 0 0 0 0 0 9 0 0 0 0 % H
% Ile: 0 0 9 0 9 0 0 0 0 0 9 0 0 0 0 % I
% Lys: 0 0 0 0 9 9 17 9 9 9 0 17 0 42 9 % K
% Leu: 9 0 17 0 0 17 9 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 17 17 9 0 0 0 0 0 17 17 0 9 % N
% Pro: 9 0 0 0 42 0 0 0 17 9 17 17 9 0 9 % P
% Gln: 0 0 25 0 0 0 0 9 0 9 0 9 0 0 0 % Q
% Arg: 9 0 17 9 0 0 0 0 0 42 9 0 9 9 0 % R
% Ser: 0 0 9 0 0 0 17 25 9 17 0 25 9 9 9 % S
% Thr: 9 9 0 9 0 9 0 9 0 0 9 0 0 0 9 % T
% Val: 0 0 0 0 0 0 0 9 0 0 0 0 0 9 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 17 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _