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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ING2 All Species: 14.55
Human Site: S143 Identified Species: 29.09
UniProt: Q9H160 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H160 NP_001555.1 280 32808 S143 D K A K M D S S Q P E R S S R
Chimpanzee Pan troglodytes XP_001139734 262 29553 R132 A D K P N S K R S R R Q R N N
Rhesus Macaque Macaca mulatta XP_001084274 279 31903 E143 G E A A A Q A E K P N S K R S
Dog Lupus familis XP_540031 280 32729 S143 D K G K M D S S Q P E R S S R
Cat Felis silvestris
Mouse Mus musculus Q9ESK4 281 32974 S144 D K S K M D S S Q P E R S S R
Rat Rattus norvegicus Q498T3 421 46906 S205 N A Y N V N S S Q P L A S Y N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515013 363 40927 Q225 A K N E T M G Q A E K P N N K
Chicken Gallus gallus Q5ZKY4 249 28538 S125 S S D Y D S S S S K G K K K G
Frog Xenopus laevis Q7ZX31 416 46165 S205 N V Y N V N S S Q P L T S Y N
Zebra Danio Brachydanio rerio NP_001002448 278 32265 A132 E K V R H D P A S T S T N V M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394517 279 32379 M132 R R T R T E T M V E S S N T M
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792118 254 29513 K130 P D P P S K T K K A V P V V V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 52.1 60.7 97.5 N.A. 96.8 22.5 N.A. 45.1 34.2 23.3 72.5 N.A. N.A. 42.1 N.A. 41.4
Protein Similarity: 100 67.8 77.5 97.8 N.A. 98.5 39.9 N.A. 58.1 52.5 40.6 83.2 N.A. N.A. 62.1 N.A. 59.2
P-Site Identity: 100 0 13.3 93.3 N.A. 93.3 33.3 N.A. 6.6 13.3 33.3 13.3 N.A. N.A. 0 N.A. 0
P-Site Similarity: 100 13.3 33.3 93.3 N.A. 100 53.3 N.A. 40 20 53.3 40 N.A. N.A. 40 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 9 17 9 9 0 9 9 9 9 0 9 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 25 17 9 0 9 34 0 0 0 0 0 0 0 0 0 % D
% Glu: 9 9 0 9 0 9 0 9 0 17 25 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 0 9 0 0 0 9 0 0 0 9 0 0 0 9 % G
% His: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 42 9 25 0 9 9 9 17 9 9 9 17 9 9 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 17 0 0 0 0 % L
% Met: 0 0 0 0 25 9 0 9 0 0 0 0 0 0 17 % M
% Asn: 17 0 9 17 9 17 0 0 0 0 9 0 25 17 25 % N
% Pro: 9 0 9 17 0 0 9 0 0 50 0 17 0 0 0 % P
% Gln: 0 0 0 0 0 9 0 9 42 0 0 9 0 0 0 % Q
% Arg: 9 9 0 17 0 0 0 9 0 9 9 25 9 9 25 % R
% Ser: 9 9 9 0 9 17 50 50 25 0 17 17 42 25 9 % S
% Thr: 0 0 9 0 17 0 17 0 0 9 0 17 0 9 0 % T
% Val: 0 9 9 0 17 0 0 0 9 0 9 0 9 17 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 17 9 0 0 0 0 0 0 0 0 0 17 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _