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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SIL1 All Species: 16.06
Human Site: T51 Identified Species: 35.33
UniProt: Q9H173 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H173 NP_001032722.1 461 52085 T51 E K S S T K E T E R K E T K A
Chimpanzee Pan troglodytes XP_001157060 728 80143 T318 E K S S T K E T E R K E T K A
Rhesus Macaque Macaca mulatta XP_001114077 461 51991 T51 E K S S T K E T E R K E T K A
Dog Lupus familis XP_531925 475 53449 A61 E K S S T K E A E R K D T T A
Cat Felis silvestris
Mouse Mus musculus Q9EPK6 465 52411 S51 E K S I H Q E S D T K E T R E
Rat Rattus norvegicus Q6P6S4 465 52331 S51 E K S T H E D S D T K E T R R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_414514 467 52210 G56 E E S D I K D G S G K E P I A
Frog Xenopus laevis Q6NUA7 456 52303 N50 T E A E D D G N V E A I V E N
Zebra Danio Brachydanio rerio XP_696722 462 52311 N50 K E D S D D L N N A K E T H L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VBV5 429 47924 A48 Q T I A E G Q A I P R G L H V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789880 684 78062 E53 E S D T Y K K E E L K E R L A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 62.3 96.7 89.4 N.A. 84.9 85.1 N.A. N.A. 59.5 49.4 47.4 N.A. 28.2 N.A. N.A. 25.5
Protein Similarity: 100 62.9 97.8 92.8 N.A. 90.5 91.6 N.A. N.A. 76.2 69.1 69.9 N.A. 45.1 N.A. N.A. 42.5
P-Site Identity: 100 100 100 80 N.A. 46.6 40 N.A. N.A. 40 0 26.6 N.A. 0 N.A. N.A. 40
P-Site Similarity: 100 100 100 86.6 N.A. 73.3 80 N.A. N.A. 53.3 20 40 N.A. 26.6 N.A. N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 10 0 0 0 19 0 10 10 0 0 0 55 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 19 10 19 19 19 0 19 0 0 10 0 0 0 % D
% Glu: 73 28 0 10 10 10 46 10 46 10 0 73 0 10 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 10 10 10 0 10 0 10 0 0 0 % G
% His: 0 0 0 0 19 0 0 0 0 0 0 0 0 19 0 % H
% Ile: 0 0 10 10 10 0 0 0 10 0 0 10 0 10 0 % I
% Lys: 10 55 0 0 0 55 10 0 0 0 82 0 0 28 0 % K
% Leu: 0 0 0 0 0 0 10 0 0 10 0 0 10 10 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 19 10 0 0 0 0 0 10 % N
% Pro: 0 0 0 0 0 0 0 0 0 10 0 0 10 0 0 % P
% Gln: 10 0 0 0 0 10 10 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 37 10 0 10 19 10 % R
% Ser: 0 10 64 46 0 0 0 19 10 0 0 0 0 0 0 % S
% Thr: 10 10 0 19 37 0 0 28 0 19 0 0 64 10 0 % T
% Val: 0 0 0 0 0 0 0 0 10 0 0 0 10 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _