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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METTL9
All Species:
18.79
Human Site:
S275
Identified Species:
31.79
UniProt:
Q9H1A3
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H1A3
NP_001070648.1
318
36536
S275
N
W
E
E
Q
V
N
S
L
P
E
V
F
R
K
Chimpanzee
Pan troglodytes
XP_001160038
277
32344
R240
N
S
L
P
E
V
F
R
K
A
G
F
V
I
E
Rhesus Macaque
Macaca mulatta
XP_001086688
323
36436
Q281
N
L
L
D
R
C
D
Q
P
L
T
L
L
K
D
Dog
Lupus familis
XP_536936
277
32398
R240
N
S
L
P
E
V
F
R
K
A
G
F
V
I
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9EPL4
318
36407
S275
N
W
E
E
Q
V
N
S
L
P
E
V
F
R
K
Rat
Rattus norvegicus
NP_001156636
318
36423
S275
N
W
E
E
Q
V
N
S
L
P
E
V
F
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508171
357
41002
L304
D
V
I
S
C
L
N
L
L
D
R
C
D
Q
P
Chicken
Gallus gallus
Q5ZMH6
321
36990
S278
T
W
E
E
Q
V
N
S
L
P
E
V
F
G
K
Frog
Xenopus laevis
NP_001079600
315
36737
S272
V
W
E
E
Q
V
N
S
L
A
N
V
F
H
E
Zebra Danio
Brachydanio rerio
NP_001070810
234
26336
A197
V
V
G
S
A
E
A
A
H
P
G
S
G
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611846
305
34724
N267
R
F
M
E
L
L
E
N
C
G
Y
R
V
E
A
Honey Bee
Apis mellifera
XP_623513
379
42710
L291
L
E
G
Q
I
A
S
L
V
D
R
V
F
A
P
Nematode Worm
Caenorhab. elegans
NP_508880
311
35470
Y271
D
M
N
N
S
A
Y
Y
L
P
D
A
I
F
L
Sea Urchin
Strong. purpuratus
XP_001188574
325
37619
Y277
R
S
F
S
R
V
P
Y
L
C
E
G
D
A
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.9
78.9
83.6
N.A.
97.1
97.4
N.A.
61
86.9
72.9
39.9
N.A.
32.3
35.8
37.1
46.7
Protein Similarity:
100
84.9
79.2
84.2
N.A.
99.3
99
N.A.
64.4
90.6
83.6
49.6
N.A.
50
52.2
53.7
62.7
P-Site Identity:
100
13.3
6.6
13.3
N.A.
100
100
N.A.
13.3
86.6
66.6
6.6
N.A.
6.6
13.3
13.3
20
P-Site Similarity:
100
26.6
40
26.6
N.A.
100
100
N.A.
33.3
86.6
73.3
20
N.A.
26.6
33.3
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
15
8
8
0
22
0
8
0
15
8
% A
% Cys:
0
0
0
0
8
8
0
0
8
8
0
8
0
0
0
% C
% Asp:
15
0
0
8
0
0
8
0
0
15
8
0
15
0
8
% D
% Glu:
0
8
36
43
15
8
8
0
0
0
36
0
0
15
29
% E
% Phe:
0
8
8
0
0
0
15
0
0
0
0
15
43
8
0
% F
% Gly:
0
0
15
0
0
0
0
0
0
8
22
8
8
8
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% H
% Ile:
0
0
8
0
8
0
0
0
0
0
0
0
8
15
0
% I
% Lys:
0
0
0
0
0
0
0
0
15
0
0
0
0
8
29
% K
% Leu:
8
8
22
0
8
15
0
15
58
8
0
8
8
0
8
% L
% Met:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
43
0
8
8
0
0
43
8
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
15
0
0
8
0
8
43
0
0
0
0
15
% P
% Gln:
0
0
0
8
36
0
0
8
0
0
0
0
0
8
0
% Q
% Arg:
15
0
0
0
15
0
0
15
0
0
15
8
0
22
0
% R
% Ser:
0
22
0
22
8
0
8
36
0
0
0
8
0
0
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% T
% Val:
15
15
0
0
0
58
0
0
8
0
0
43
22
0
0
% V
% Trp:
0
36
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
15
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _