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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: METTL9 All Species: 11.21
Human Site: T37 Identified Species: 18.97
UniProt: Q9H1A3 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H1A3 NP_001070648.1 318 36536 T37 R S L Y V N M T S G P G G P A
Chimpanzee Pan troglodytes XP_001160038 277 32344 W8 M D R K T T S W D T K F Y E K
Rhesus Macaque Macaca mulatta XP_001086688 323 36436 G35 R T R W L E L G R W R L W P E
Dog Lupus familis XP_536936 277 32398 W8 M D R R I T S W D T K F Y E K
Cat Felis silvestris
Mouse Mus musculus Q9EPL4 318 36407 T37 R S L Y V N M T S G P G G P A
Rat Rattus norvegicus NP_001156636 318 36423 T37 R S L Y V N M T S G P G G P A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508171 357 41002 R39 E R G R H C Y R A G E G E R R
Chicken Gallus gallus Q5ZMH6 321 36990 M43 R S L Y A N M M G S H G P P A
Frog Xenopus laevis NP_001079600 315 36737 S34 L R S H L S R S L Y M N M M S
Zebra Danio Brachydanio rerio NP_001070810 234 26336
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611846 305 34724 C34 I D T R K W Y C L N H E L P P
Honey Bee Apis mellifera XP_623513 379 42710 A44 Y R P H G S L A R L L Y D K Q
Nematode Worm Caenorhab. elegans NP_508880 311 35470 S34 A Q N L F A A S L P D G E T Q
Sea Urchin Strong. purpuratus XP_001188574 325 37619 V34 N L R K Y Y D V E K W Y R C D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.9 78.9 83.6 N.A. 97.1 97.4 N.A. 61 86.9 72.9 39.9 N.A. 32.3 35.8 37.1 46.7
Protein Similarity: 100 84.9 79.2 84.2 N.A. 99.3 99 N.A. 64.4 90.6 83.6 49.6 N.A. 50 52.2 53.7 62.7
P-Site Identity: 100 0 13.3 0 N.A. 100 100 N.A. 13.3 60 0 0 N.A. 6.6 0 6.6 0
P-Site Similarity: 100 0 40 6.6 N.A. 100 100 N.A. 20 60 33.3 0 N.A. 6.6 20 13.3 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 8 8 8 8 8 0 0 0 0 0 29 % A
% Cys: 0 0 0 0 0 8 0 8 0 0 0 0 0 8 0 % C
% Asp: 0 22 0 0 0 0 8 0 15 0 8 0 8 0 8 % D
% Glu: 8 0 0 0 0 8 0 0 8 0 8 8 15 15 8 % E
% Phe: 0 0 0 0 8 0 0 0 0 0 0 15 0 0 0 % F
% Gly: 0 0 8 0 8 0 0 8 8 29 0 43 22 0 0 % G
% His: 0 0 0 15 8 0 0 0 0 0 15 0 0 0 0 % H
% Ile: 8 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 15 8 0 0 0 0 8 15 0 0 8 15 % K
% Leu: 8 8 29 8 15 0 15 0 22 8 8 8 8 0 0 % L
% Met: 15 0 0 0 0 0 29 8 0 0 8 0 8 8 0 % M
% Asn: 8 0 8 0 0 29 0 0 0 8 0 8 0 0 0 % N
% Pro: 0 0 8 0 0 0 0 0 0 8 22 0 8 43 8 % P
% Gln: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 15 % Q
% Arg: 36 22 29 22 0 0 8 8 15 0 8 0 8 8 8 % R
% Ser: 0 29 8 0 0 15 15 15 22 8 0 0 0 0 8 % S
% Thr: 0 8 8 0 8 15 0 22 0 15 0 0 0 8 0 % T
% Val: 0 0 0 0 22 0 0 8 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 8 0 8 0 15 0 8 8 0 8 0 0 % W
% Tyr: 8 0 0 29 8 8 15 0 0 8 0 15 15 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _