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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ANAPC1 All Species: 16.06
Human Site: S1000 Identified Species: 32.12
UniProt: Q9H1A4 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H1A4 NP_073153.1 1944 216500 S1000 P K G K S V L S S D V P S G T
Chimpanzee Pan troglodytes XP_515601 1394 155989 P505 R V N V V Q Y P E L S D H E F
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532958 1943 216470 S999 P K G K S V L S S D V P S G T
Cat Felis silvestris
Mouse Mus musculus P53995 1944 216068 S1000 P R G K S V L S S E V S S G T
Rat Rattus norvegicus NP_001101241 1944 216060 S1000 P R G K S V L S S D V A S G A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_419303 1945 216100 L1001 L K S K S V M L S S D S P S G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001921168 1979 220132 G1043 A N R K S T V G L N V M L E P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573025 2030 227256 A1068 Y K E D S L S A R C P P T G G
Honey Bee Apis mellifera XP_001122449 1939 218025 K995 N H L E N E G K N Y S I K D P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001202400 910 100394 S21 L R R R Q S V S A F P S D F T
Poplar Tree Populus trichocarpa XP_002312165 1929 212815 S1017 A P L Q G K V S R T W I I Y N
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_196175 1678 186257 S789 L S V F R N F S S S K E F E M
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 71.5 N.A. 97.3 N.A. 92.1 92.9 N.A. N.A. 81.7 N.A. 66 N.A. 33.6 38 N.A. 25.2
Protein Similarity: 100 71.5 N.A. 98.5 N.A. 96 96.5 N.A. N.A. 90.2 N.A. 79 N.A. 52.2 59.1 N.A. 33.8
P-Site Identity: 100 0 N.A. 100 N.A. 80 80 N.A. N.A. 33.3 N.A. 20 N.A. 26.6 0 N.A. 13.3
P-Site Similarity: 100 0 N.A. 100 N.A. 93.3 86.6 N.A. N.A. 40 N.A. 33.3 N.A. 46.6 20 N.A. 40
Percent
Protein Identity: 28.5 N.A. N.A. 27.2 N.A. N.A.
Protein Similarity: 47 N.A. N.A. 45.8 N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: 20 N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 0 0 0 0 0 9 9 0 0 9 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % C
% Asp: 0 0 0 9 0 0 0 0 0 25 9 9 9 9 0 % D
% Glu: 0 0 9 9 0 9 0 0 9 9 0 9 0 25 0 % E
% Phe: 0 0 0 9 0 0 9 0 0 9 0 0 9 9 9 % F
% Gly: 0 0 34 0 9 0 9 9 0 0 0 0 0 42 17 % G
% His: 0 9 0 0 0 0 0 0 0 0 0 0 9 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 17 9 0 0 % I
% Lys: 0 34 0 50 0 9 0 9 0 0 9 0 9 0 0 % K
% Leu: 25 0 17 0 0 9 34 9 9 9 0 0 9 0 0 % L
% Met: 0 0 0 0 0 0 9 0 0 0 0 9 0 0 9 % M
% Asn: 9 9 9 0 9 9 0 0 9 9 0 0 0 0 9 % N
% Pro: 34 9 0 0 0 0 0 9 0 0 17 25 9 0 17 % P
% Gln: 0 0 0 9 9 9 0 0 0 0 0 0 0 0 0 % Q
% Arg: 9 25 17 9 9 0 0 0 17 0 0 0 0 0 0 % R
% Ser: 0 9 9 0 59 9 9 59 50 17 17 25 34 9 0 % S
% Thr: 0 0 0 0 0 9 0 0 0 9 0 0 9 0 34 % T
% Val: 0 9 9 9 9 42 25 0 0 0 42 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % W
% Tyr: 9 0 0 0 0 0 9 0 0 9 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _