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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ANAPC1 All Species: 25.76
Human Site: S1240 Identified Species: 51.52
UniProt: Q9H1A4 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H1A4 NP_073153.1 1944 216500 S1240 P A L L P P T S T E L D V P H
Chimpanzee Pan troglodytes XP_515601 1394 155989 D740 P E M E Y C T D R E S Y S L A
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532958 1943 216470 S1239 P A L L P P T S T E L D V P H
Cat Felis silvestris
Mouse Mus musculus P53995 1944 216068 S1240 P A L L P P T S T E L D V P H
Rat Rattus norvegicus NP_001101241 1944 216060 S1240 P A L L P P T S T E L D V P H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_419303 1945 216100 S1242 P A L L P P T S T E L D V P H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001921168 1979 220132 S1287 P A L L P P T S T E L D V P H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573025 2030 227256 A1313 E A L L P A T A M E L D I P Q
Honey Bee Apis mellifera XP_001122449 1939 218025 S1230 E T L L P P T S I E L N V Q Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001202400 910 100394 G256 G E I G R P P G P E L N N C T
Poplar Tree Populus trichocarpa XP_002312165 1929 212815 V1261 T H F D L Q Y V R P D F I M L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_196175 1678 186257 F1024 D I A K A L F F H V P A R Y Q
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 71.5 N.A. 97.3 N.A. 92.1 92.9 N.A. N.A. 81.7 N.A. 66 N.A. 33.6 38 N.A. 25.2
Protein Similarity: 100 71.5 N.A. 98.5 N.A. 96 96.5 N.A. N.A. 90.2 N.A. 79 N.A. 52.2 59.1 N.A. 33.8
P-Site Identity: 100 20 N.A. 100 N.A. 100 100 N.A. N.A. 100 N.A. 100 N.A. 60 60 N.A. 20
P-Site Similarity: 100 26.6 N.A. 100 N.A. 100 100 N.A. N.A. 100 N.A. 100 N.A. 73.3 66.6 N.A. 33.3
Percent
Protein Identity: 28.5 N.A. N.A. 27.2 N.A. N.A.
Protein Similarity: 47 N.A. N.A. 45.8 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 6.6 N.A. N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 59 9 0 9 9 0 9 0 0 0 9 0 0 9 % A
% Cys: 0 0 0 0 0 9 0 0 0 0 0 0 0 9 0 % C
% Asp: 9 0 0 9 0 0 0 9 0 0 9 59 0 0 0 % D
% Glu: 17 17 0 9 0 0 0 0 0 84 0 0 0 0 0 % E
% Phe: 0 0 9 0 0 0 9 9 0 0 0 9 0 0 0 % F
% Gly: 9 0 0 9 0 0 0 9 0 0 0 0 0 0 0 % G
% His: 0 9 0 0 0 0 0 0 9 0 0 0 0 0 50 % H
% Ile: 0 9 9 0 0 0 0 0 9 0 0 0 17 0 0 % I
% Lys: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 67 67 9 9 0 0 0 0 75 0 0 9 9 % L
% Met: 0 0 9 0 0 0 0 0 9 0 0 0 0 9 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 17 9 0 0 % N
% Pro: 59 0 0 0 67 67 9 0 9 9 9 0 0 59 0 % P
% Gln: 0 0 0 0 0 9 0 0 0 0 0 0 0 9 25 % Q
% Arg: 0 0 0 0 9 0 0 0 17 0 0 0 9 0 0 % R
% Ser: 0 0 0 0 0 0 0 59 0 0 9 0 9 0 0 % S
% Thr: 9 9 0 0 0 0 75 0 50 0 0 0 0 0 9 % T
% Val: 0 0 0 0 0 0 0 9 0 9 0 0 59 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 9 0 9 0 0 0 0 9 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _