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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ANAPC1 All Species: 18.79
Human Site: S1449 Identified Species: 37.58
UniProt: Q9H1A4 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H1A4 NP_073153.1 1944 216500 S1449 S E I E L P C S E D L N L E T
Chimpanzee Pan troglodytes XP_515601 1394 155989 K940 S A F N C L H K F A K D F M T
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532958 1943 216470 S1448 S E I E L P C S E D L N L E T
Cat Felis silvestris
Mouse Mus musculus P53995 1944 216068 S1449 S E I E L P C S E D L N L E T
Rat Rattus norvegicus NP_001101241 1944 216060 S1449 S E I E L P C S E D L N L E T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_419303 1945 216100 S1451 H A T E L P S S E D L S L E T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001921168 1979 220132 D1496 D Q T P V S E D L N M E T L V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573025 2030 227256 P1522 F Y E N E Y A P E D Y D V D Y
Honey Bee Apis mellifera XP_001122449 1939 218025 N1436 P T S E I G Q N V D L E T M N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001202400 910 100394 S456 C A Y D C L L S Y L K K L M N
Poplar Tree Populus trichocarpa XP_002312165 1929 212815 T1468 T L Y P R L P T V P N D N R C
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_196175 1678 186257 V1224 Q S Q V P E V V K N G I S Q L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 71.5 N.A. 97.3 N.A. 92.1 92.9 N.A. N.A. 81.7 N.A. 66 N.A. 33.6 38 N.A. 25.2
Protein Similarity: 100 71.5 N.A. 98.5 N.A. 96 96.5 N.A. N.A. 90.2 N.A. 79 N.A. 52.2 59.1 N.A. 33.8
P-Site Identity: 100 13.3 N.A. 100 N.A. 100 100 N.A. N.A. 66.6 N.A. 0 N.A. 13.3 20 N.A. 13.3
P-Site Similarity: 100 20 N.A. 100 N.A. 100 100 N.A. N.A. 73.3 N.A. 26.6 N.A. 33.3 33.3 N.A. 20
Percent
Protein Identity: 28.5 N.A. N.A. 27.2 N.A. N.A.
Protein Similarity: 47 N.A. N.A. 45.8 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 20 N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 25 0 0 0 0 9 0 0 9 0 0 0 0 0 % A
% Cys: 9 0 0 0 17 0 34 0 0 0 0 0 0 0 9 % C
% Asp: 9 0 0 9 0 0 0 9 0 59 0 25 0 9 0 % D
% Glu: 0 34 9 50 9 9 9 0 50 0 0 17 0 42 0 % E
% Phe: 9 0 9 0 0 0 0 0 9 0 0 0 9 0 0 % F
% Gly: 0 0 0 0 0 9 0 0 0 0 9 0 0 0 0 % G
% His: 9 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 34 0 9 0 0 0 0 0 0 9 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 9 9 0 17 9 0 0 0 % K
% Leu: 0 9 0 0 42 25 9 0 9 9 50 0 50 9 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 9 0 0 25 0 % M
% Asn: 0 0 0 17 0 0 0 9 0 17 9 34 9 0 17 % N
% Pro: 9 0 0 17 9 42 9 9 0 9 0 0 0 0 0 % P
% Gln: 9 9 9 0 0 0 9 0 0 0 0 0 0 9 0 % Q
% Arg: 0 0 0 0 9 0 0 0 0 0 0 0 0 9 0 % R
% Ser: 42 9 9 0 0 9 9 50 0 0 0 9 9 0 0 % S
% Thr: 9 9 17 0 0 0 0 9 0 0 0 0 17 0 50 % T
% Val: 0 0 0 9 9 0 9 9 17 0 0 0 9 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 17 0 0 9 0 0 9 0 9 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _