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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANAPC1
All Species:
18.79
Human Site:
S194
Identified Species:
37.58
UniProt:
Q9H1A4
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H1A4
NP_073153.1
1944
216500
S194
L
L
F
E
R
S
A
S
S
H
E
V
P
P
G
Chimpanzee
Pan troglodytes
XP_515601
1394
155989
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532958
1943
216470
S194
L
L
F
E
R
S
S
S
T
H
E
V
P
P
G
Cat
Felis silvestris
Mouse
Mus musculus
P53995
1944
216068
S194
L
L
F
E
R
C
S
S
S
H
E
V
P
P
S
Rat
Rattus norvegicus
NP_001101241
1944
216060
S194
L
L
F
E
R
S
S
S
S
H
E
V
P
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419303
1945
216100
S195
L
L
L
E
R
S
G
S
S
H
E
V
P
P
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001921168
1979
220132
I194
L
L
L
E
R
K
N
I
T
V
D
G
H
M
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573025
2030
227256
S239
L
L
L
E
K
D
S
S
N
A
L
I
S
H
M
Honey Bee
Apis mellifera
XP_001122449
1939
218025
V179
I
L
L
E
K
T
Q
V
P
I
S
E
I
R
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202400
910
100394
Poplar Tree
Populus trichocarpa
XP_002312165
1929
212815
R179
C
D
M
S
R
A
K
R
E
I
V
H
S
P
H
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_196175
1678
186257
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.5
N.A.
97.3
N.A.
92.1
92.9
N.A.
N.A.
81.7
N.A.
66
N.A.
33.6
38
N.A.
25.2
Protein Similarity:
100
71.5
N.A.
98.5
N.A.
96
96.5
N.A.
N.A.
90.2
N.A.
79
N.A.
52.2
59.1
N.A.
33.8
P-Site Identity:
100
0
N.A.
86.6
N.A.
80
86.6
N.A.
N.A.
80
N.A.
26.6
N.A.
26.6
13.3
N.A.
0
P-Site Similarity:
100
0
N.A.
100
N.A.
86.6
93.3
N.A.
N.A.
80
N.A.
40
N.A.
53.3
33.3
N.A.
0
Percent
Protein Identity:
28.5
N.A.
N.A.
27.2
N.A.
N.A.
Protein Similarity:
47
N.A.
N.A.
45.8
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
9
0
0
9
0
0
0
0
0
% A
% Cys:
9
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
9
0
0
0
0
9
0
0
0
0
% D
% Glu:
0
0
0
67
0
0
0
0
9
0
42
9
0
0
0
% E
% Phe:
0
0
34
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
9
0
0
0
0
9
0
0
17
% G
% His:
0
0
0
0
0
0
0
0
0
42
0
9
9
9
9
% H
% Ile:
9
0
0
0
0
0
0
9
0
17
0
9
9
0
0
% I
% Lys:
0
0
0
0
17
9
9
0
0
0
0
0
0
0
0
% K
% Leu:
59
67
34
0
0
0
0
0
0
0
9
0
0
0
0
% L
% Met:
0
0
9
0
0
0
0
0
0
0
0
0
0
9
9
% M
% Asn:
0
0
0
0
0
0
9
0
9
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
9
0
0
0
42
50
0
% P
% Gln:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
59
0
0
9
0
0
0
0
0
9
0
% R
% Ser:
0
0
0
9
0
34
34
50
34
0
9
0
17
0
34
% S
% Thr:
0
0
0
0
0
9
0
0
17
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
9
0
9
9
42
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _