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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ANAPC1 All Species: 23.03
Human Site: S876 Identified Species: 46.06
UniProt: Q9H1A4 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H1A4 NP_073153.1 1944 216500 S876 R S R L V V L S I A L Y I L G
Chimpanzee Pan troglodytes XP_515601 1394 155989 W383 L A E R L V V W M T N V G F T
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532958 1943 216470 S875 R S R L V V L S I A L Y I L G
Cat Felis silvestris
Mouse Mus musculus P53995 1944 216068 S876 R S R L V V L S I A L Y T L G
Rat Rattus norvegicus NP_001101241 1944 216060 S876 R S R L V V L S I A L Y T L G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_419303 1945 216100 S877 R S K L V I L S V A L Y V L G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001921168 1979 220132 S918 R T K L L V L S Y A L Y V V G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573025 2030 227256 Q939 E R S R I L L Q L V S L V T H
Honey Bee Apis mellifera XP_001122449 1939 218025 L871 K T K N I I Y L M A L I A N E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001202400 910 100394
Poplar Tree Populus trichocarpa XP_002312165 1929 212815 N885 Y G R D Q R L N E V R R L L C
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_196175 1678 186257 T667 L R R G C L S T N F D D L P D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 71.5 N.A. 97.3 N.A. 92.1 92.9 N.A. N.A. 81.7 N.A. 66 N.A. 33.6 38 N.A. 25.2
Protein Similarity: 100 71.5 N.A. 98.5 N.A. 96 96.5 N.A. N.A. 90.2 N.A. 79 N.A. 52.2 59.1 N.A. 33.8
P-Site Identity: 100 6.6 N.A. 100 N.A. 93.3 93.3 N.A. N.A. 73.3 N.A. 60 N.A. 6.6 13.3 N.A. 0
P-Site Similarity: 100 33.3 N.A. 100 N.A. 93.3 93.3 N.A. N.A. 100 N.A. 93.3 N.A. 33.3 53.3 N.A. 0
Percent
Protein Identity: 28.5 N.A. N.A. 27.2 N.A. N.A.
Protein Similarity: 47 N.A. N.A. 45.8 N.A. N.A.
P-Site Identity: 20 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 33.3 N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 0 0 0 0 59 0 0 9 0 0 % A
% Cys: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 9 % C
% Asp: 0 0 0 9 0 0 0 0 0 0 9 9 0 0 9 % D
% Glu: 9 0 9 0 0 0 0 0 9 0 0 0 0 0 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 9 0 0 0 9 0 % F
% Gly: 0 9 0 9 0 0 0 0 0 0 0 0 9 0 50 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % H
% Ile: 0 0 0 0 17 17 0 0 34 0 0 9 17 0 0 % I
% Lys: 9 0 25 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 17 0 0 50 17 17 67 9 9 0 59 9 17 50 0 % L
% Met: 0 0 0 0 0 0 0 0 17 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 0 0 0 9 9 0 9 0 0 9 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % P
% Gln: 0 0 0 0 9 0 0 9 0 0 0 0 0 0 0 % Q
% Arg: 50 17 50 17 0 9 0 0 0 0 9 9 0 0 0 % R
% Ser: 0 42 9 0 0 0 9 50 0 0 9 0 0 0 0 % S
% Thr: 0 17 0 0 0 0 0 9 0 9 0 0 17 9 9 % T
% Val: 0 0 0 0 42 50 9 0 9 17 0 9 25 9 0 % V
% Trp: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 0 9 0 9 0 0 50 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _