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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ANAPC1 All Species: 22.73
Human Site: T1241 Identified Species: 45.45
UniProt: Q9H1A4 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H1A4 NP_073153.1 1944 216500 T1241 A L L P P T S T E L D V P H N
Chimpanzee Pan troglodytes XP_515601 1394 155989 R741 E M E Y C T D R E S Y S L A A
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532958 1943 216470 T1240 A L L P P T S T E L D V P H N
Cat Felis silvestris
Mouse Mus musculus P53995 1944 216068 T1241 A L L P P T S T E L D V P H N
Rat Rattus norvegicus NP_001101241 1944 216060 T1241 A L L P P T S T E L D V P H N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_419303 1945 216100 T1243 A L L P P T S T E L D V P H N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001921168 1979 220132 T1288 A L L P P T S T E L D V P H S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573025 2030 227256 M1314 A L L P A T A M E L D I P Q S
Honey Bee Apis mellifera XP_001122449 1939 218025 I1231 T L L P P T S I E L N V Q Q N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001202400 910 100394 P257 E I G R P P G P E L N N C T N
Poplar Tree Populus trichocarpa XP_002312165 1929 212815 R1262 H F D L Q Y V R P D F I M L R
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_196175 1678 186257 H1025 I A K A L F F H V P A R Y Q A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 71.5 N.A. 97.3 N.A. 92.1 92.9 N.A. N.A. 81.7 N.A. 66 N.A. 33.6 38 N.A. 25.2
Protein Similarity: 100 71.5 N.A. 98.5 N.A. 96 96.5 N.A. N.A. 90.2 N.A. 79 N.A. 52.2 59.1 N.A. 33.8
P-Site Identity: 100 13.3 N.A. 100 N.A. 100 100 N.A. N.A. 100 N.A. 93.3 N.A. 60 66.6 N.A. 26.6
P-Site Similarity: 100 20 N.A. 100 N.A. 100 100 N.A. N.A. 100 N.A. 100 N.A. 80 73.3 N.A. 40
Percent
Protein Identity: 28.5 N.A. N.A. 27.2 N.A. N.A.
Protein Similarity: 47 N.A. N.A. 45.8 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 6.6 N.A. N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 59 9 0 9 9 0 9 0 0 0 9 0 0 9 17 % A
% Cys: 0 0 0 0 9 0 0 0 0 0 0 0 9 0 0 % C
% Asp: 0 0 9 0 0 0 9 0 0 9 59 0 0 0 0 % D
% Glu: 17 0 9 0 0 0 0 0 84 0 0 0 0 0 0 % E
% Phe: 0 9 0 0 0 9 9 0 0 0 9 0 0 0 0 % F
% Gly: 0 0 9 0 0 0 9 0 0 0 0 0 0 0 0 % G
% His: 9 0 0 0 0 0 0 9 0 0 0 0 0 50 0 % H
% Ile: 9 9 0 0 0 0 0 9 0 0 0 17 0 0 0 % I
% Lys: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 67 67 9 9 0 0 0 0 75 0 0 9 9 0 % L
% Met: 0 9 0 0 0 0 0 9 0 0 0 0 9 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 17 9 0 0 59 % N
% Pro: 0 0 0 67 67 9 0 9 9 9 0 0 59 0 0 % P
% Gln: 0 0 0 0 9 0 0 0 0 0 0 0 9 25 0 % Q
% Arg: 0 0 0 9 0 0 0 17 0 0 0 9 0 0 9 % R
% Ser: 0 0 0 0 0 0 59 0 0 9 0 9 0 0 17 % S
% Thr: 9 0 0 0 0 75 0 50 0 0 0 0 0 9 0 % T
% Val: 0 0 0 0 0 0 9 0 9 0 0 59 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 9 0 0 0 0 9 0 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _