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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NXF5
All Species:
21.52
Human Site:
S178
Identified Species:
59.17
UniProt:
Q9H1B4
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H1B4
NP_116564
397
45628
S178
L
Y
Q
L
D
G
L
S
D
I
T
E
K
A
P
Chimpanzee
Pan troglodytes
XP_001134768
626
71505
S289
L
Y
Q
L
D
G
L
S
D
I
T
E
K
A
P
Rhesus Macaque
Macaca mulatta
XP_001094356
760
86437
S423
L
Y
Q
L
D
G
L
S
D
I
I
E
K
A
P
Dog
Lupus familis
XP_549146
615
70268
S281
L
Y
G
L
D
G
L
S
D
I
I
E
M
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q99JX7
618
70282
S283
L
Y
K
L
D
D
M
S
S
I
V
Q
K
A
P
Rat
Rattus norvegicus
O88984
618
70343
S283
L
Y
K
L
D
D
M
S
S
I
V
Q
K
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923961
642
71544
V306
L
F
R
L
D
D
L
V
D
I
I
H
K
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U1H9
672
76230
K273
I
S
S
M
E
A
F
K
G
V
E
K
R
L
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XVS7
628
70944
S263
I
R
H
L
D
Y
A
S
A
L
V
S
I
A
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.3
43.4
42.1
N.A.
35.1
35.5
N.A.
N.A.
N.A.
N.A.
28.9
N.A.
20.9
N.A.
21.5
N.A.
Protein Similarity:
100
56.5
46.9
52
N.A.
48.2
47
N.A.
N.A.
N.A.
N.A.
40.9
N.A.
34.6
N.A.
35.5
N.A.
P-Site Identity:
100
100
93.3
80
N.A.
60
60
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
6.6
N.A.
26.6
N.A.
P-Site Similarity:
100
100
93.3
80
N.A.
80
80
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
46.6
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
12
12
0
12
0
0
0
0
78
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
89
34
0
0
56
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
12
0
0
0
0
0
12
45
0
0
0
% E
% Phe:
0
12
0
0
0
0
12
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
12
0
0
45
0
0
12
0
0
0
0
0
0
% G
% His:
0
0
12
0
0
0
0
0
0
0
0
12
0
0
0
% H
% Ile:
23
0
0
0
0
0
0
0
0
78
34
0
12
0
0
% I
% Lys:
0
0
23
0
0
0
0
12
0
0
0
12
67
0
12
% K
% Leu:
78
0
0
89
0
0
56
0
0
12
0
0
0
12
0
% L
% Met:
0
0
0
12
0
0
23
0
0
0
0
0
12
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
89
% P
% Gln:
0
0
34
0
0
0
0
0
0
0
0
23
0
0
0
% Q
% Arg:
0
12
12
0
0
0
0
0
0
0
0
0
12
0
0
% R
% Ser:
0
12
12
0
0
0
0
78
23
0
0
12
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
23
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
12
0
12
34
0
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
67
0
0
0
12
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _