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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EAP1
All Species:
18.18
Human Site:
Y423
Identified Species:
44.44
UniProt:
Q9H1B7
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H1B7
NP_078772.1
796
82659
Y423
E
L
K
L
F
I
E
Y
P
T
G
S
G
N
V
Chimpanzee
Pan troglodytes
XP_510088
790
81943
Y417
E
L
K
L
F
I
E
Y
P
T
G
S
G
N
V
Rhesus Macaque
Macaca mulatta
Q2MJS2
794
82427
Y421
E
L
K
L
F
I
E
Y
P
T
G
S
G
N
V
Dog
Lupus familis
XP_541548
584
61625
G251
V
R
F
K
K
D
H
G
L
V
G
R
V
F
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8K3X4
775
80546
Y402
E
L
K
L
F
I
E
Y
P
T
G
S
G
N
V
Rat
Rattus norvegicus
Q5EIC4
783
81477
Y410
E
L
K
L
F
I
E
Y
P
T
G
S
G
N
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426978
534
54591
V201
A
Q
Q
Q
L
N
H
V
D
A
S
S
K
A
A
Frog
Xenopus laevis
Q66IY8
690
72623
E357
S
S
G
F
K
Y
L
E
Y
E
K
K
H
G
S
Zebra Danio
Brachydanio rerio
Q1LV17
605
64887
V272
A
F
D
A
K
L
M
V
E
F
E
L
K
I
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784488
661
71839
D328
V
A
K
Q
M
Y
Q
D
C
V
K
D
I
G
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
99.1
44.2
N.A.
94.9
95.9
N.A.
N.A.
35.1
67.3
46.8
N.A.
N.A.
N.A.
N.A.
43.4
Protein Similarity:
100
98.1
99.3
53.8
N.A.
95.7
96.4
N.A.
N.A.
42.8
73.1
56.4
N.A.
N.A.
N.A.
N.A.
54.1
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
N.A.
6.6
0
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
6.6
N.A.
100
100
N.A.
N.A.
13.3
0
6.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
10
0
10
0
0
0
0
0
10
0
0
0
10
20
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
10
0
10
10
0
0
10
0
0
0
% D
% Glu:
50
0
0
0
0
0
50
10
10
10
10
0
0
0
0
% E
% Phe:
0
10
10
10
50
0
0
0
0
10
0
0
0
10
10
% F
% Gly:
0
0
10
0
0
0
0
10
0
0
60
0
50
20
0
% G
% His:
0
0
0
0
0
0
20
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
0
50
0
0
0
0
0
0
10
10
0
% I
% Lys:
0
0
60
10
30
0
0
0
0
0
20
10
20
0
10
% K
% Leu:
0
50
0
50
10
10
10
0
10
0
0
10
0
0
0
% L
% Met:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
0
0
0
50
0
% N
% Pro:
0
0
0
0
0
0
0
0
50
0
0
0
0
0
0
% P
% Gln:
0
10
10
20
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% R
% Ser:
10
10
0
0
0
0
0
0
0
0
10
60
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
50
0
0
0
0
0
% T
% Val:
20
0
0
0
0
0
0
20
0
20
0
0
10
0
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
20
0
50
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _