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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUCKS1
All Species:
27.88
Human Site:
S229
Identified Species:
68.15
UniProt:
Q9H1E3
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H1E3
NP_073568.2
243
27296
S229
T
S
P
P
P
E
K
S
G
D
E
G
S
E
D
Chimpanzee
Pan troglodytes
XP_514141
243
27342
S229
T
S
P
P
P
E
K
S
G
D
E
G
S
E
D
Rhesus Macaque
Macaca mulatta
XP_001100185
311
34457
P290
K
R
P
K
W
V
P
P
G
M
A
F
L
S
S
Dog
Lupus familis
XP_536103
297
32946
S283
A
S
P
P
P
E
K
S
G
D
E
G
S
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q80XU3
234
26295
G221
S
P
P
E
K
K
S
G
D
E
G
S
E
D
E
Rat
Rattus norvegicus
Q9EPJ0
243
27122
S229
A
S
P
P
L
E
K
S
G
D
E
G
S
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508086
538
59213
S524
A
S
P
P
P
E
K
S
G
D
E
G
S
E
D
Chicken
Gallus gallus
NP_998746
292
32576
S278
A
S
P
P
P
E
K
S
G
D
E
G
S
E
E
Frog
Xenopus laevis
NP_001084711
293
32980
S279
T
S
S
P
Q
E
K
S
G
D
D
V
S
D
E
Zebra Danio
Brachydanio rerio
NP_001004601
305
34125
T279
E
S
P
P
S
K
K
T
K
D
E
A
P
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
25
80.1
N.A.
92.1
95
N.A.
42.3
77.4
65.1
51.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
45
80.4
N.A.
93.8
97.1
N.A.
43.8
80.4
72
63.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
13.3
93.3
N.A.
6.6
86.6
N.A.
93.3
86.6
60
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
13.3
93.3
N.A.
40
86.6
N.A.
93.3
93.3
80
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
40
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
80
10
0
0
20
60
% D
% Glu:
10
0
0
10
0
70
0
0
0
10
70
0
10
70
30
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
80
0
10
60
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
10
10
20
80
0
10
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
90
80
50
0
10
10
0
0
0
0
10
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
80
10
0
10
0
10
70
0
0
0
10
70
10
10
% S
% Thr:
30
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _